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International Journal of Otolaryngology
Volume 2012 (2012), Article ID 216592, 4 pages
http://dx.doi.org/10.1155/2012/216592
Research Article

Acute-Phase Inflammatory Response in Idiopathic Sudden Deafness: Pathogenic Implications

1UGC Otorhinolaryngology, Virgen del Rocio University Hospital, C/Manuel Siurot s/n, 41013 Seville, Spain
2Faculty of Medicine, University of Seville, C/Doctor Fedriani s/n, 41009 Seville, Spain

Received 30 April 2012; Revised 13 October 2012; Accepted 19 October 2012

Academic Editor: Leonard P. Rybak

Copyright © 2012 Miguel A. López-González et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. B. E. Schreiber, C. Agrup, D. O. Haskard, and L. M. Luxon, “Sudden sensorineural hearing loss,” The Lancet, vol. 375, no. 9721, pp. 1203–1211, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. H. Lee, B. H. Ahn, and R. W. Baloh, “Sudden deafness with vertigo as a sole manifestation of anterior inferior cerebellar artery infarction,” Journal of the Neurological Sciences, vol. 222, no. 1-2, pp. 105–107, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. T. Murakami, H. Nakayasu, M. Doi et al., “Anterior and posterior inferior cerebellar artery infarction with sudden deafness and vertigo,” Journal of Clinical Neuroscience, vol. 13, no. 10, pp. 1051–1054, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. E. J. Son, J. H. Bang, and J. G. Kang, “Anterior inferior cerebellar artery infarction presenting with sudden hearing loss and vertigo,” Laryngoscope, vol. 117, no. 3, pp. 556–558, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. C. Gerace and C. Pianura, “Sudden deafness without vertigo as a sole manifestation of AICA infarct,” Neurological Sciences, vol. 29, no. 5, pp. 371–372, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. M. Tamhankar and D. Solomon, “Acute hearing loss,” Current Treatment Options in Neurology, vol. 6, no. 1, pp. 55–65, 2004. View at Google Scholar · View at Scopus
  7. M. Tomita and Y. Fukuuchi, “Leukocytes, macrophages and secondary brain damage following cerebral ischemia,” Acta Neurochirurgica, Supplement, vol. 1996, no. 66, pp. 32–39, 1996. View at Google Scholar · View at Scopus
  8. A. M. Ross, P. Hurn, N. Perrin, L. Wood, W. Carlini, and K. Potempa, “Evidence of the peripheral inflammatory response in patients with transient ischemic attack,” Journal of Stroke and Cerebrovascular Diseases, vol. 16, no. 5, pp. 203–207, 2007. View at Publisher · View at Google Scholar · View at Scopus
  9. H. C. A. Emsley, C. J. Smith, P. J. Tyrrell, and S. J. Hopkins, “Inflammation in acute ischemic stroke and its relevance to stroke critical care,” Neurocritical Care, vol. 9, no. 1, pp. 125–138, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. I. Moxon-Emre and L. C. Schlichter, “Evolution of inflammation and white matter injury in a model of transient focal ischemia,” Journal of Neuropathology and Experimental Neurology, vol. 69, no. 1, pp. 1–15, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. J. C. Adams, “Clinical implications of inflammatory cytokines in the cochlea: a technical note,” Otology and Neurotology, vol. 23, no. 3, pp. 316–322, 2002. View at Google Scholar · View at Scopus
  12. J. Y. Um, C. H. Jang, H. L. Kim et al., “Proinflammatory cytokine IL-1 â polymorphisms in sudden sensorineural hearing loss,” Immunopharmacology & Immunotoxicology. In press. View at Publisher · View at Google Scholar
  13. S. I. Nam, E. Ha, K. H. Jung et al., “IL4 receptor polymorphism is associated with increased risk of sudden deafness in Korean population,” Life Sciences, vol. 78, no. 6, pp. 664–667, 2006. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Hiramatsu, M. Teranishi, Y. Uchida et al., “Polymorphisms in genes involved in inflammatory pathways in patients with sudden sensorineural hearing loss,” Journal of Neurogenetics. In press. View at Publisher · View at Google Scholar
  15. M. Masuda, S. Kanzaki, S. Minami et al., “Correlations of inflammatory biomarkers with the onset and prognosis of idiopathic sudden sensorineural hearing loss,” Otology & Neurotology, vol. 33, pp. 1142–1150, 2012. View at Google Scholar
  16. S. I. Nam, G. I. Yu, H. J. Kim et al., “A polymorphism at -1607 2G in the matrix metalloproteinase-1 (MMP-1) increased risk of sudden deafness in korean population but not at -519A/G in MMP-1,” Laryngoscope, vol. 121, no. 1, pp. 171–175, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. N. Hato, J. Hyodo, S. Takeda et al., “Local hypothermia in the treatment of idiopathic sudden sensorineural hearing loss,” Auris Nasus Larynx, vol. 37, no. 5, pp. 626–630, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. M. Grgić, V. Petric, M. P. Grgić, V. Demarin, and B. Pegan, “Doppler ultrasonography of the vertebrobasilar circulation in patients with sudden sensorineural hearing loss,” Journal of Otolaryngology, vol. 34, no. 1, pp. 51–59, 2005. View at Google Scholar · View at Scopus
  19. A. De Kleyn, “Sudden complete or partial loss of function of the octavus system in apparently normal persons,” Acta Oto-Laryngologica, vol. 32, pp. 407–429, 1944. View at Google Scholar
  20. W. R. Wilson, R. W. Veltri, N. Laird, and P. M. Sprinkle, “Viral and epidemiologic studies of idiopathic sudden hearing loss,” Otolaryngology, vol. 91, no. 6, pp. 653–658, 1983. View at Google Scholar · View at Scopus
  21. Blood differential count. MedlinePlus, 2012, http://www.nlm.nih.gov/medlineplus/ency/article/003657.htm.
  22. E. Klemm, A. Deutscher, and R. Mösges, “A present investigation of the epidemiology in idiopathic sudden sensorineural hearing loss,” Laryngo- Rhino- Otologie, vol. 88, no. 8, pp. 524–527, 2009. View at Publisher · View at Google Scholar · View at Scopus
  23. M. D. Seidman, W. S. Quirk, and N. A. Shirwany, “Mechanisms of alterations in the microcirculation of the cochlea,” Annals of the New York Academy of Sciences, vol. 884, pp. 226–232, 1999. View at Google Scholar · View at Scopus
  24. H. C. Lin, P. Z. Chao, and H. C. Lee, “Sudden sensorineural hearing loss increases the risk of stroke: a 5-year follow-up study,” Stroke, vol. 39, no. 10, pp. 2744–2748, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. G. G. Browning, “Sudden sensorineural hearing loss is a modest predictor of future stroke,” Clinical Otolaryngology, vol. 34, no. 2, p. 157, 2009. View at Publisher · View at Google Scholar · View at Scopus