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International Journal of Otolaryngology
Volume 2012 (2012), Article ID 373025, 8 pages
Clinical Study

Maxillomandibular Advancement in the Management of Obstructive Sleep Apnea

1Division of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA
2Division of Oral and Maxillofacial Surgery, Mayo Clinic, Rochester, MN 55905, USA

Received 22 July 2011; Revised 10 October 2011; Accepted 18 October 2011

Academic Editor: P. H. Dejonckere

Copyright © 2012 Ranji Varghese et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Maxillomandibular advancement (MMA) is a surgical option for obstructive sleep apnea (OSA). MMA involves forward-fixing the maxilla and mandible approximately 10  mm via Le Fort I maxillary and sagittal split mandibular osteotomies. We retrospectively reviewed outcomes from 24 consecutive OSA patients who underwent MMA at our institution. MMA resulted in an 83% reduction in the group mean apnea-hypopnea index (AHI) per polysomnography an average of 6.7 months after surgery. Forty-two percent of patients achieved a post-MMA AHI of less than 5 events/hour sleep and 71% achieved an AHI less than or equal to 10 events/hour sleep. The Epworth Sleepiness Scale score decreased by an average of 5 post-surgery. No parameters predictive of cure for OSA by MMA were identified.