The Effect of Amifostine on Submandibular Gland Histology after Radiation

Table 1

Patient demographics.

Parameter	Amifostine	Partial-amifostine	No-amifostine	𝑃-value
Number	5	9	10
Mean age	60	58	58	0.87^1
95% confidence interval	45.5–74.1	52.3–63.1	53.6–62.0
Range	45–70	50–71	48–68
Mean days since end of treatment	88	89	81	0.85^1
95% confidence interval	39.1–137.1	68.5–110.4	58.2–105.0
Range	46–134	55–151	46–139
Mean amifostine dose	17	5	0	0.0001^1
95% Confidence Interval	13–21.8	3.7–7.2	0
Range	12–21	1–9	0
Mean Pack Years	28	20	41	0.3^1
95% confidence interval	−6.2–62.2	−3.5–43.9	21.8–60.3
Range	0−70	0–87.5	0–100
Gender				1^2
Male	5	6	8
Female	0	3	2
Stage				0.40^2
IVA	4	7	9
IVB	1	2	1
Site				0.006^2
Oropharynx	5	9	5
Hypopharynx	0	0	4
Larynx	0	0	1

¹ANOVA.
²Fisher’s Exact Test.