Research Article

p16, Cyclin D1, and HIF-1α Predict Outcomes of Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Definitive Intensity-Modulated Radiation Therapy

Table 6

Tumor counts stratified by p16 and cyclin D1 staining.

Cyclin D1 (% of cells staining)
0%1–25%26–50%51–75%76–100%

p16 negative2110677
p16 positive38179840

Cochran-Armitage Trend test: .