Mucin Production and Mucous Cell Metaplasia in Otitis Media
Figure 2
Pneumococcal cell wall component peptidoglycan-polysaccharides (PGPSs) stimulate the proliferation (a) of rat middle ear epithelial cells whereas endotoxin (LPS) causes the death of the cells (b) compared with carrier treated cells (c). Cells were incubated with PGPS at 20 ng/mL for 6 hours and stained with PCNA antibody. Brown in color indicates cell nuclei with positive PCNA antigen.
