Table of Contents Author Guidelines Submit a Manuscript
International Journal of Otolaryngology
Volume 2012, Article ID 789572, 7 pages
http://dx.doi.org/10.1155/2012/789572
Review Article

Sinonasal Manifestations in Cystic Fibrosis

Divison of Pediatric Otolaryngology-Head and Neck Surgery, Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College, 428 East 72nd Street, Suite 100, New York, NY 10021, USA

Received 24 January 2012; Revised 4 June 2012; Accepted 15 June 2012

Academic Editor: Leonard P. Rybak

Copyright © 2012 Karin P. Q. Oomen and Max M. April. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. R. Riordan, J. M. Rommens, B. S. Kerem et al., “Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA,” Science, vol. 245, no. 4922, pp. 1066–1073, 1989. View at Google Scholar · View at Scopus
  2. A. Shatz, “Management of recurrent sinus disease in children with cystic fibrosis: a combined approach,” Otolaryngology, vol. 135, no. 2, pp. 248–252, 2006. View at Publisher · View at Google Scholar · View at Scopus
  3. R. Tandon and C. Derkay, “Contemporary management of rhinosinusitis and cystic fibrosis,” Current Opinion in Otolaryngology and Head and Neck Surgery, vol. 11, no. 1, pp. 41–44, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. R. Cepero, R. J. H. Smith, F. I. Catlin, K. L. Bressler, G. T. Furuta, and K. C. Shandera, “Cystic fibrosis—an otolaryngologic perspective,” Otolaryngology, vol. 97, no. 4, pp. 356–360, 1987. View at Google Scholar · View at Scopus
  5. J. D. F. Kerrebijn, R. M. L. Poublon, and S. E. Overbeek, “Nasal and paranasal disease in adult cystic fibrosis patients,” European Respiratory Journal, vol. 5, no. 10, pp. 1239–1242, 1992. View at Google Scholar · View at Scopus
  6. W. J. Fokkens, V. Lund, and J. Mullol, “European position paper on rhinosinusitis and nasal polyps 2007,” Rhinology, vol. 45, no. 20, pp. 1–136, 2007. View at Google Scholar · View at Scopus
  7. J. M. Godoy, A. N. Godoy, G. Ribalta, and I. Largo, “Bacterial pattern in chronic sinusitis and cystic fibrosis,” Otolaryngology, vol. 145, pp. 673–676, 2011. View at Publisher · View at Google Scholar
  8. V. Raman, R. Clary, K. L. Siegrist, B. Zehnbauer, and T. A. Chatila, “Increased prevalence of mutations in the cystic fibrosis transmembrane conductance regulator in children with chronic rhinosinusitis,” Pediatrics, vol. 109, no. 1, article E13, 2002. View at Google Scholar · View at Scopus
  9. X. Wang, B. Moylan, D. A. Leopold et al., “Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population,” Journal of the American Medical Association, vol. 284, no. 14, pp. 1814–1819, 2000. View at Google Scholar · View at Scopus
  10. J. P. Cuyler and A. J. Monaghan, “Cystic fibrosis and sinusitis,” Journal of Otolaryngology, vol. 18, no. 4, pp. 173–175, 1989. View at Google Scholar · View at Scopus
  11. J. M. Triglia and R. Nicollas, “Nasal and sinus polyposis in children,” Laryngoscope, vol. 107, no. 7, pp. 963–966, 1997. View at Publisher · View at Google Scholar · View at Scopus
  12. M. G. Slieker, A. G. M. Schilder, C. S. P. M. Uiterwaal, and C. K. Van der Ent, “Children with cystic fibrosis: who should visit the otorhinolaryngologist?” Archives of Otolaryngology, vol. 128, no. 11, pp. 1245–1248, 2002. View at Google Scholar · View at Scopus
  13. M. W. Ryan, “Diseases associated with chronic rhinosinusitis: what is the significance?” Current Opinion in Otolaryngology & Head and Neck Surgery, vol. 11, pp. 41–44, 2003. View at Publisher · View at Google Scholar
  14. M. W. Yung, J. Gould, and G. J. G. Upton, “Nasal polyposis in children with cystic fibrosis: a long-term follow-up study,” Annals of Otology, Rhinology and Laryngology, vol. 111, no. 12, pp. 1081–1086, 2002. View at Google Scholar · View at Scopus
  15. T. L. Smith, S. Mendolia-Loffredo, T. A. Loehrl, R. Sparapani, P. W. Laud, and A. B. Nattinger, “Predictive factors and outcomes in endoscopic sinus surgery for chronic rhinosinusitis,” Laryngoscope, vol. 115, no. 12, pp. 2199–2205, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. E. Sakano, A. F. Ribeiro, L. Barth, A. C. Neto, and J. D. Ribeiro, “Nasal and paranasal sinus endoscopy, computed tomography and microbiology of upper airways and the correlations with genotype and severity of cystic fibrosis,” International Journal of Pediatric Otorhinolaryngology, vol. 71, no. 1, pp. 41–50, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. M. M. April, S. J. Zinreich, F. M. Baroody, and R. M. Naclerio, “Coronal CT scan abnormalities in children with chronic sinusitis,” Laryngoscope, vol. 103, no. 9, pp. 985–990, 1993. View at Google Scholar · View at Scopus
  18. M. M. April, D. E. Tunkel, J. De Celie-Germana et al., “Computed tomography (CT) scan findings of the paranasal sinuses in cystic fibrosis,” American Journal of Rhinology, vol. 9, pp. 277–280, 1995. View at Publisher · View at Google Scholar
  19. M. G. Stewart, D. T. Donovan, R. B. Parke Jr., and M. H. Bautista, “Does the severity of sinus computed tomography findings predict outcome in chronic sinusitis?” Otolaryngology, vol. 123, no. 1 I, pp. 81–84, 2000. View at Google Scholar · View at Scopus
  20. P. J. Hadfield, J. M. Rowe-Jones, and I. S. Mackay, “A prospective treatment trial of nasal polyps in adults with cystic fibrosis,” Rhinology, vol. 38, no. 2, pp. 63–65, 2000. View at Google Scholar · View at Scopus
  21. K. Cheng, D. Ashby, and R. Smyth, “Oral steroids for cystic fibrosis,” Cochrane Database of Systematic Reviews, no. 2, Article ID CD000407, 2000. View at Google Scholar · View at Scopus
  22. T. Van Zele, P. Gevaert, G. Holtappels et al., “Oral steroids and doxycycline: two different approaches to treat nasal polyps,” Journal of Allergy and Clinical Immunology, vol. 125, no. 5, pp. 1069–1076, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. S. Vaidyanathan, M. Barnes, P. Williamson, P. Hopkinson, P. T. Donnan, and B. Lipworth, “Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial,” Annals of Internal Medicine, vol. 154, no. 5, pp. 293–302, 2011. View at Google Scholar · View at Scopus
  24. B. W. Ramsey, J. Davies, N. G. McElvaney, E. Tullis et al., “A CFTR potentiator in patients with cystic fibrosis and the G551D mutation,” The New England Journal of Medicine, vol. 365, pp. 1663–1672, 2011. View at Publisher · View at Google Scholar
  25. G. L. D. S. Franche, F. Abreu E Silva, and C. D. S. Saleh, “Bacteriology of the middle meatus aspirate in patients with cystic fibrosis,” Brazilian Journal of Otorhinolaryngology, vol. 73, no. 4, pp. 494–499, 2007. View at Google Scholar · View at Scopus
  26. E. D. Shapiro, G. J. Milmoe, and E. R. Wald, “Bacteriology of the maxillary sinuses in patients with cystic fibrosis,” Journal of Infectious Diseases, vol. 146, no. 5, pp. 589–593, 1982. View at Google Scholar · View at Scopus
  27. C. R. Hansen, T. Pressler, C. Koch, and N. Høiby, “Long-term azitromycin treatment of cystic fibrosis patients with chronic Pseudomonas aeruginosa infection; an observational cohort study,” Journal of Cystic Fibrosis, vol. 4, no. 1, pp. 35–40, 2005. View at Publisher · View at Google Scholar · View at Scopus
  28. V. B. Pai and M. C. Nahata, “Efficacy and safety of aerosolized tobramycin in cystic fibrosis,” Pediatric Pulmonology, vol. 32, no. 4, pp. 314–327, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. E. M. Westerman, P. P. H. Le Brun, D. J. Touw, H. W. Frijlink, and H. G. M. Heijerman, “Effect of nebulized colistin sulphate and colistin sulphomethate on lung function in patients with cystic fibrosis: a pilot study,” Journal of Cystic Fibrosis, vol. 3, no. 1, pp. 23–28, 2004. View at Publisher · View at Google Scholar · View at Scopus
  30. K. S. McCoy, A. L. Quittner, C. M. Oermann, R. L. Gibson, G. Z. Retsch-Bogart, and A. B. Montgomery, “Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis,” American Journal of Respiratory and Critical Care Medicine, vol. 178, no. 9, pp. 921–928, 2008. View at Publisher · View at Google Scholar · View at Scopus
  31. K. H. V. Tan, M. Mulheran, A. J. Knox, and A. R. Smyth, “Aminoglycoside prescribing and surveillance in cystic fibrosis,” American Journal of Respiratory and Critical Care Medicine, vol. 167, no. 6, pp. 819–823, 2003. View at Publisher · View at Google Scholar · View at Scopus
  32. T. Yamada, S. Fujieda, S. Mori, H. Yamamoto, and H. Saito, “Macrolide treatment decreased the size of nasal polyps and IL-8 levels in nasal lavage,” American Journal of Rhinology, vol. 14, no. 3, pp. 143–148, 2000. View at Google Scholar · View at Scopus
  33. M. B. Jorissen, K. De Boeck, and H. Cuppens, “Genotype-phenotype correlations for the paranasal sinuses in cystic fibrosis,” American Journal of Respiratory and Critical Care Medicine, vol. 159, no. 5, pp. 1412–1416, 1999. View at Google Scholar · View at Scopus
  34. H. Shwachman, L. L. Kulzycki, H. L. Mueller, and C. G. Flake, “Nasal polyposis in patients with cystic fibrosis,” Pediatrics, vol. 30, pp. 389–401, 1962. View at Google Scholar · View at Scopus
  35. B. F. Jaffe, M. Strome, K. T. Khaw, and H. Shwachman, “Nasal polypectomy and sinus surgery for cystic fibrosis a 10 year review,” Otolaryngologic Clinics of North America, vol. 10, no. 1, pp. 81–90, 1977. View at Google Scholar · View at Scopus
  36. D. M. Crockett, T. J. McGill, G. B. Healy, E. M. Friedman, and L. J. Salkeld, “Nasal and paranasal sinus surgery in children with cystic fibrosis,” Annals of Otology, Rhinology and Laryngology, vol. 96, no. 4, pp. 367–372, 1987. View at Google Scholar · View at Scopus
  37. T. Keck and A. Rozsasi, “Medium-term symptom outcomes after paranasal sinus surgery in children and young adults with cystic fibrosis,” Laryngoscope, vol. 117, no. 3, pp. 475–479, 2007. View at Publisher · View at Google Scholar · View at Scopus
  38. F. D. Albritton and T. T. Kingdom, “Endoscopic sinus surgery in patients with cystic fibrosis: an analysis of complications,” American Journal of Rhinology, vol. 14, no. 6, pp. 379–385, 2000. View at Google Scholar · View at Scopus
  39. D. L. Schulte and J. L. Kasperbauer, “Safety of paranasal sinus surgery in patients with cystic fibrosis,” Laryngoscope, vol. 108, no. 12, pp. 1813–1815, 1998. View at Google Scholar · View at Scopus
  40. J. P. Cuyler, “Follow-up of endoscopic sinus surgery on children with cystic fibrosis,” Archives of Otolaryngology, vol. 118, no. 5, pp. 505–506, 1992. View at Google Scholar · View at Scopus
  41. G. J. Nishioka, G. J. Barbero, P. Konig, D. S. Parsons, P. R. Cook, and W. E. Davis, “Symptom outcome after functional endoscopic sinus surgery in patients with cystic fibrosis: a prospective study,” Otolaryngology, vol. 113, no. 4, pp. 440–445, 1995. View at Publisher · View at Google Scholar · View at Scopus
  42. J. W. Jones, D. S. Parsons, and J. P. Cuyler, “The results of functional endoscopic sinus (FES) surgery on the symptoms of patients with cystic fibrosis,” International Journal of Pediatric Otorhinolaryngology, vol. 28, no. 1, pp. 25–32, 1993. View at Publisher · View at Google Scholar · View at Scopus
  43. A. N. Khalid, J. Mace, and T. L. Smith, “Outcomes of sinus surgery in adults with cystic fibrosis,” Otolaryngology, vol. 141, no. 3, pp. 358–363, 2009. View at Publisher · View at Google Scholar · View at Scopus
  44. R. B. Moss and V. V. King, “Management of sinusitis in cystic fibrosis by endoscopic surgery and serial antimicrobial lavage: reduction in recurrence requiring surgery,” Archives of Otolaryngology, vol. 121, no. 5, pp. 566–572, 1995. View at Google Scholar · View at Scopus
  45. C. Georgalas, F. Hansen, W. M. J. Videler, and W. J. Fokkens, “Long term results of Draf type III, (modified endoscopic Lothrop) frontal sinus drainage procedure in 122 patients: a single centre experience,” Rhinology, vol. 49, pp. 195–201, 2011. View at Google Scholar
  46. A. E. Stewart and W. C. Vaughan, “Balloon sinuplasty versus surgical management of chronic rhinosinusitis,” Current Allergy and Asthma Reports, vol. 10, no. 3, pp. 181–187, 2010. View at Publisher · View at Google Scholar · View at Scopus
  47. H. H. Ramadan, “Safety and feasibility of balloon sinuplasty for treatment of chronic rhinosinusitis in children,” Annals of Otology, Rhinology and Laryngology, vol. 118, no. 3, pp. 161–165, 2009. View at Google Scholar · View at Scopus
  48. H. H. Ramadan, K. McLaughlin, G. Josephson, F. Rimell, J. Bent, and S. R. Parikh, “Balloon catheter sinuplasty in young children,” American Journal of Rhinology and Allergy, vol. 24, no. 1, pp. e54–e56, 2010. View at Publisher · View at Google Scholar · View at Scopus
  49. H. H. Ramadan and A. M. Terrell, “Balloon catheter sinuplasty and adenoidectomy in children with chronic rhinosinusitis,” Annals of Otology, Rhinology and Laryngology, vol. 119, no. 9, pp. 578–582, 2010. View at Google Scholar · View at Scopus
  50. A. R. Sedaghat and M. J. Cunningham, “Does balloon catheter sinuplasty have a role in the surgical management of pediatric sinus disease?” Laryngoscope, vol. 121, pp. 2053–2054, 2011. View at Publisher · View at Google Scholar
  51. S. S. Becker, A. De Alarcon, S. R. Bomeli, J. K. Han, and C. W. Gross, “Risk factors for recurrent sinus surgery in cystic fibrosis: review of a decade of experience,” American Journal of Rhinology, vol. 21, no. 4, pp. 478–482, 2007. View at Publisher · View at Google Scholar · View at Scopus
  52. J. M. Rowe-Jones and I. S. Mackay, “Endoscopic sinus surgery in the treatment of cystic fibrosis with nasal polyposis,” Laryngoscope, vol. 106, no. 12, pp. 1540–1544, 1996. View at Google Scholar · View at Scopus
  53. S. Rickert, V. E. Banuchi, J. D. Germana, M. G. Stewart, and M. M. April, “Cystic fibrosis and endoscopic sinus surgery: relationship between nasal polyposis and likelihood of revision endoscopic sinus surgery in patients with cystic fibrosis,” Archives of Otolaryngology, vol. 136, no. 10, pp. 988–992, 2010. View at Publisher · View at Google Scholar · View at Scopus
  54. V. G. Gentile and G. Isaacson, “Patterns of sinusitis in cystic fibrosis,” Laryngoscope, vol. 106, no. 8, pp. 1005–1009, 1996. View at Google Scholar · View at Scopus
  55. D. T. Umetsu, R. B. Moss, V. V. King, and N. J. Lewiston, “Sinus disease in patients with severe cystic fibrosis: relation to pulmonary exacerbation,” The Lancet, vol. 335, no. 8697, pp. 1077–1078, 1990. View at Publisher · View at Google Scholar · View at Scopus
  56. D. Madonna, G. Isaacson, R. M. Rosenfeld, and H. Panitch, “Effect of sinus surgery on pulmonary function in patients with cystic fibrosis,” Laryngoscope, vol. 107, no. 3, pp. 328–331, 1997. View at Publisher · View at Google Scholar · View at Scopus
  57. K. W. Rosbe, D. T. Jones, R. Rahbar, T. Lahiri, and A. D. Auerbach, “Endoscopic sinus surgery in cystic fibrosis: do patients benefit from surgery?” International Journal of Pediatric Otorhinolaryngology, vol. 61, no. 2, pp. 113–119, 2001. View at Publisher · View at Google Scholar · View at Scopus
  58. A. J. Osborn, R. Leung, F. Ratjen, and A. L. James, “Effect of endoscopic sinus surgery on pulmonary function and microbial pathogens in a pediatric population with cystic fibrosis,” Archives of Otolaryngology, vol. 137, no. 6, pp. 542–547, 2011. View at Publisher · View at Google Scholar · View at Scopus
  59. D. C. Lanza and D. W. Kennedy, “Adult rhinosinusitis defined,” Otolaryngology, vol. 117, pp. S1–S7, 1997. View at Google Scholar · View at Scopus