Mucin Gene Expression in Reflux Laryngeal Mucosa: Histological and In Situ Hybridization Observations

Table 3

Mucin gene expression in control versus reflux laryngeal mucosa.

Laryngeal mucosa	MUC1		MUC2		MUC3		MUC4		MUC5AC
	Control	LPR	Control	LPR	Control	LPR	Control	LPR	Control	LPR
Posterior commissure	0/3	4/26	0/3	6/26	2/3	15/26	2/3	17/24	2/3	3/24
Ventricle	1/3	4/22	1/3	5/20	2/3	11/20	3/3	14/20	3/3	3/24
Vocal folds	0/3	7/22	0/3	3/22	2/3	9/21	2/3	14/21	1/3	5/21
Total/average	1/9	15/70	1/9	14/68	6/9	35/67	7/9	45/65	6/9	11/69
	11%	21%	11%	29%	67%	52%	78%	69%	67%	16%

Numbers of mucosal samples for each area of laryngeal mucosa expressing the mucin gene in question are divided by total numbers of samples studied and resultant % calculated. LPR: laryngopharyngeal reflux mucosa.