Table 1: Diagnoses of sphenoid lesions.

Group diagnosisFrequency (%)Detail

Infection/inflammationBacterial sphenoiditis40 (32.8%)One with a supraclinoid ICA aneurysm
Fungal sphenoiditis48 (39.3%)37 fungal balls, 11 invasive
Other inflammation10 (8.2%)Two resolved sphenoiditis, two chronic inflammation, two retention cysts, one mucocele, one polyp, one Tuberculosis (TB), one
TumorBenign, benign fibroosseous lesion12 (9.8%)Three fibrous dysplasias, three pituitary adenomas, two meningiomas, two inverted papillomas, one giant cell tumor, one neuroendocrine tumor
Malignant12 (9.8%)Two plasmacytomas, one myeloid sarcoma, one adenocarcinoma, one breast cancer, one melanoma, one neuroblastoma, one chordoma, one poorly differentiated carcinoma (CA), one squamous cell CA, one lymphoma, one neuroendocrine CA

pseudoaneurysm case presented with clinical meningitis. On his brain CT scan, a pseudoaneurysm of the cavernous segment of the internal carotid artery (ICA) was found with an extension into the cloudy sphenoid sinus. After a 2-week course of intravenous antibiotics and surgical clipping of the supraclinoid ICA and bypass (common carotid artery-middle cerebral artery), his sphenoiditis resolved without surgical drainage.