Research Article

Good Clinical Approach: Delphi Consensus for the Use of Betahistine in Menière’s Disease

Table 2

Results of the Consensus Conference on the use and dosage of betahistine during the acute attacks of MD. 1 = absolutely disagree, 2 = disagree, 3 = agree, 4 = more than agree, and 5 = absolutely agree. Consensus was reached when the sum of items 1 and 2 or 3, 4, and 5 reached 66%. Same asterisk convention.

During an attack, referred to the vertigo in the Menière’s disease do you think that betahistine:

1. Is the first-choice drug in monotherapy47%27%16%5%5%

7426

2. Is useful when associated to other therapies14%14%47%23%2%

2872

3. Is not useful17%17%46%3%17%

3466

4. Shows poor efficacy9%3%48%9%31%

1288

If you use Betahistine during acute attacks, what is the dosage?

1. I do not use betahistine during acute attacks10 %17 %34 %19 %20 %

2773

2. Range from 8 to 32 mg/day44 %43 %13 %0 %0 %

8713

3. Range from 32 to 48 mg/day19 %28 %38 %9 %6 %

4753

4. Higher than 48 mg/day30 %20 %34 %13 %3 %

5050