Research Article

Good Clinical Approach: Delphi Consensus for the Use of Betahistine in Menière’s Disease

Table 9

Results of the Consensus Conference on the parameters to be used to evaluate betahistine efficacy. 1 = absolutely disagree, 2 = disagree, 3 = agree, 4 = more than agree, and 5 = absolutely agree. Consensus was reached when the sum of items 1 and 2 or 3, 4, and 5 reached 66%. Same asterisk convention.

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In your opinion, what are the best parameters of efficacy to evaluate usage of Betahistine in the Ménière’s disease treatment?

Intensity or severity of attacks (vertigo score)2%0%40%17%41%

2%98%

Number of attacks for 6 months0%0%36%19%45%

0%100%

Quality of life questionnaires0%4%55%11%30%

4%96%

Days of work/number of days being disabled2%22%60%8%8%

24%76%

Intensity of attacks in last 6 moths4%17%52%5%22%

21%79%

Questionnaire on social impact of Meniere disease3%18%50%12%17%

21%79%

Questionnaire DHI2%5%60%10%23%

7%93%

Audiogram17%31%41%4%7%

48%52%