International Journal of Otolaryngology / 2019 / Article / Tab 1

Research Article

Persistent Unilateral Sore Throat: Should It Be Included in the 2-Week Wait Referral Criteria by NICE

Table 1

Symptoms suspecting cancer for urgent referral.

DoH 2000 GuidelinesNICE Guidelines 2005NICE Guidelines 2015

Ulceration of oral mucosa persisting for > 3 weeksUlceration of oral mucosa persisting for > 3 weeksUlceration of oral mucosa persisting for > 3 weeks

All red or red and white patches of the oral mucosaUnexplained red and white patches
(including suspected lichen planus) of the oral mucosa
A red or red and white patch in the oral cavity consistent with erythroplakia or
erythroleukoplakia

Hoarseness persisting for >6 weeksHoarseness persists for more than 3 weeksAged 45 or above persistent unexplained hoarseness

Unresolving neck masses for > 3 weeksUnresolving neck lump for > 3 weeksPersistent unexplained lump in the neck

Unexplained tooth mobility not associated with periodontal diseaseUnexplained tooth mobility not associated with periodontal diseaseLump in the lip or oral cavity

Unilateral nasal obstruction particularly when associated with purulent dischargeUnexplained persistent sore or painful throat

Cranial neuropathiesPersistent swelling in the parotid or
submandibular gland

Orbital massesUnilateral unexplained pain in the head and neck
area for more than 4 weeks, associated with otalgia but with normal otoscopy

Dysphagia persisting for 3 weeks

Oral swellings persisting for > 3 weeks

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