Melatonin Exerts Anti-Inflammatory, Antioxidant, and Neuromodulatory Effects That Could Potentially Be Useful in the Treatment of Vertigo

Table 1

Melatonin effects on neurotransmitters.

Neurotransmitter	Vestibular receptors	Melatonin action	Effect
GABA	GABA-A	Stimulation	Sedative
	GABA-B		Anxiolytic
Dopamine	D1	Inhibition	Sedative
	D2		Antiemetic
Substance P	NK1R	Inhibition	Anti-inflammatory
			Anti-migraine
CGRP	CALCRL	Inhibition	Anti-inflammatory
			Anti-migraine