Outcomes of Endolymphatic Sac Surgery for Meniere’s Disease with and without Comorbid Migraine

Table 3

Outcomes for endolymphatic sac surgery stratified by migraine as a comorbidity.

Variable	MD + M^a (N = 6^c)	MD − M^b (N = 42^c)	P value [95% CI]
Preoperative baseline
Frequency of major vertigo episodes (per month)	11.2 ± 10.1	16.6 ± 16.7	0.30 [−16.7, 5.6],
Duration of major vertigo episodes (minutes)	143 ± 73.4	393.4 ± 600.7	0.02^s [−458.9, −42.0]
Functional level scale	1.8 ± 0.96	2.9 ± 1.83	0.09 [−2.6, 0.25]
1995 AAO vertigo control
Class A	2 (33.33%)	21 (50.00%)
Class B	2 (33.33%)	13 (30.95%)
Class C	0 (0.00%)	1 (2.38%)
Class D	2 (33.33%)	2 (4.76%)
Class E	0 (0.00%)	0 (0.00%)
Class F	0 (0.00%)	5 (11.90%)
Good control: classes A-B	4 (66.67%)	34 (80.95%)	0.59
Poor control: classes C–F	2 (33.33%)	8 (19.05%)
Mean vertigo control (%)	32.8 ± 48.9	34.0 ± 65.8	0.96 [−48.4, 51.2]

^aMeniere’s disease with migraine. ^bMeniere’s disease without migraine. ^cPatients with available data in accordance with time intervals specified by 1995 AAO Guidelines. Two-sample t-test. Fisher’s exact test. ^SSignificant at 5% level of significance.