Assessment of DNA Damage after Photodynamic Therapy Using a Metallophthalocyanine Photosensitizer

Figure 1

Human lung cancer cells (A549), Human breast cancer cell (MCF7) and Human esophageal cancer cells (SNO) under light microscope with 40X magnification showing a dramatic reduction of the cell viability in PDT groups and a less dramatic effect on cell viability in cells pre-sensitized. This is also visible when studying the morphology of the cells where PDT treated cells show cells rounding and releasing from the flask indicative of cell death.