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International Journal of Photoenergy
Volume 2012 (2012), Article ID 759205, 9 pages
http://dx.doi.org/10.1155/2012/759205
Research Article

Influence of the Human Skin Tumor Type in Photodynamic Therapy Analysed by a Predictive Model

Applied Optical Techniques Group, TEISA Department, University of Cantabria, Avenida de los Castros S/N, 39005 Santander, Spain

Received 29 July 2011; Accepted 26 September 2011

Academic Editor: David Worrall

Copyright © 2012 I. Salas-García et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Vo-Dinh, Biomedical Photonics Handbook, CRC Press, Boca Raton, Fla, USA, 2003.
  2. M. R. Hamblin and P. Mroz, Advances in Photodynamic Therapy: Basic, Translational and Clinical, Engineering in medicine & Biology, Artech House, Norwood, Mass, USA, 2008.
  3. P. M. Prajapati, Y. Shah, and D. J. Sen, “Photodynamic therapy in cancer treatment,” Pharma Times, vol. 42, no. 5, pp. 11–15, 2010. View at Google Scholar · View at Scopus
  4. F. Fanjul-Vélez, I. Salas-García, L. A. Fernández-Fernández et al., “Photochemical model of photodynamic therapy applied to skin diseases by a topical photosensitizer,” in Therapeutic Laser Applications and Laser-Tissue Interactions IV, vol. 7373 of Proceedings of SPIE, Munich, Germany, 2009. View at Publisher · View at Google Scholar
  5. S. Kawauchi, Y. Morimoto, S. Sato et al., “Differences between cytotoxicity in photodynamic therapy using a pulsed laser and a continuous wave laser: study of oxygen consumption and photobleaching,” Lasers in Medical Science, vol. 18, no. 4, pp. 179–183, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  6. A. E. O'Connor, W. M. Gallagher, and A. T. Byrne, “Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy,” Photochemistry and Photobiology, vol. 85, no. 5, pp. 1053–1074, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  7. F. Fanjul-Vélez, O. G. Romanov, M. López-Escobar, N. Ortega-Quijano, and J. L. Arce-Diego, “Necrosis prediction of photodynamic therapy applied to skin disorders,” in Photonic Therapeutics and Diagnostics V, vol. 7161 of Proceedings of SPIE, San Jose, Calif, USA, January 2009. View at Publisher · View at Google Scholar
  8. T. H. Foster, R. S. Murant, R. G. Bryant, R. S. Knox, S. L. Gibson, and R. Hilf, “Oxygen consumption and diffusion effects in photodynamic therapy,” Radiation Research, vol. 126, no. 3, pp. 296–303, 1991. View at Google Scholar · View at Scopus
  9. X. H. Hu, Y. Feng, J. Q. Lu et al., “Modeling of a type II photofrin-mediated photodynamic therapy process in a heterogeneous tissue phantom,” Photochemistry and Photobiology, vol. 81, no. 6, pp. 1460–1468, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  10. L. Wang, S. L. Jacques, and L. Zheng, “MCML—Monte Carlo modeling of light transport in multi-layered tissues,” Computer Methods and Programs in Biomedicine, vol. 47, no. 2, pp. 131–146, 1995. View at Publisher · View at Google Scholar · View at Scopus
  11. T. C. Zhu, J. C. Finlay, X. Zhou, and J. Li, “Macroscopic modeling of the singlet oxygen production during PDT,” in Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XVI, vol. 6427 of Proceedings of SPIE, January 2007. View at Publisher · View at Google Scholar
  12. F. S. De Rosa, R. F. Vianna Lopez, J. A. Thomazine, A. C. Tedesco, N. Lange, and M. V. L. Badra Bentley, “In vitro metabolism of 5-ALA esters derivatives in hairless mice skin homogenate and in vivo PpIX accumulation studies,” Pharmaceutical Research, vol. 21, no. 12, pp. 2247–2252, 2004. View at Publisher · View at Google Scholar · View at Scopus
  13. H. S. Gill, S. N. Andrews, S. K. Sakthivel et al., “Selective removal of stratum corneum by microdermabrasion to increase skin permeability,” European Journal of Pharmaceutical Sciences, vol. 38, no. 2, pp. 95–103, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  14. J. S. Dysart and M. S. Patterson, “Characterization of Photofrin photobleaching for singlet oxygen dose estimation during photodynamic therapy of MLL cells in vitro,” Physics in Medicine and Biology, vol. 50, no. 11, pp. 2597–2616, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  15. K. K. H. Wang, W. J. Cottrell, S. Mitra, A. R. Oseroff, and T. H. Foster, “Simulations of measured photobleaching kinetics in human basal cell carcinomas suggest blood flow reductions during ALA-PDT,” Lasers in Surgery and Medicine, vol. 41, no. 9, pp. 689–696, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  16. B. Liu, T. J. Farrell, and M. S. Patterson, “A dynamic model for ALA-PDT of skin: simulation of temporal and spatial distributions of ground-state oxygen, photosensitizer and singlet oxygen,” Physics in Medicine and Biology, vol. 55, no. 19, pp. 5913–5932, 2010. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  17. L. Wang, S. L. Jacques, and L. Zheng, “CONV—convolution for responses to a finite diameter photon beam incident on multi-layered tissues,” Computer Methods and Programs in Biomedicine, vol. 54, no. 3, pp. 141–150, 1997. View at Publisher · View at Google Scholar · View at Scopus
  18. L. O. Svaasand, P. Wyss, M. T. Wyss, Y. Tadir, B. J. Tromberg, and M. W. Berns, “Dosimetry model for photodynamic therapy with topically administered photosensitizers,” Lasers in Surgery and Medicine, vol. 18, no. 2, pp. 139–149, 1996. View at Publisher · View at Google Scholar · View at Scopus
  19. E. Salomatina, B. Jiang, J. Novak, and A. N. Yaroslavsky, “Optical properties of normal and cancerous human skin in the visible and near-infrared spectral range,” Journal of Biomedical Optics, vol. 11, no. 6, Article ID 064026, 2006. View at Publisher · View at Google Scholar · View at PubMed
  20. F. Fanjul-Vélez, O. G. Romanov, and J. L. Arce-Diego, “Efficient 3D numerical approach for temperature prediction in laser irradiated biological tissues,” Computers in Biology and Medicine, vol. 39, no. 9, pp. 810–817, 2009. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  21. R. F. Donnelly, P. A. McCarron, and A. D. Woolfson, “Derivatives of 5-aminolevulinic acid for photodynamic therapy,” Perspectives in Medicinal Chemistry, vol. 1, pp. 49–63, 2007. View at Google Scholar
  22. T. Theodossiou and A. J. MacRobert, “Comparison of the photodynamic effect of exogenous photoprotoporphyrin and protoporphyrin IX on PAM 212 murine keratinocytes,” Photochemistry and Photobiology, vol. 76, no. 5, pp. 530–537, 2002. View at Publisher · View at Google Scholar · View at Scopus
  23. M. Kress, T. Meier, R. Steiner et al., “Time-resolved microspectrofluorometry and fluorescence lifetime imaging of photosensitizers using picosecond pulsed diode lasers in laser scanning microscopes,” Journal of Biomedical Optics, vol. 8, no. 1, pp. 26–32, 2003. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  24. M. Niedre, M. S. Patterson, and B. C. Wilson, “Direct near-infrared luminescence detection of singlet oxygen generated by photodynamic therapy in cells in vitro and tissues in vivo,” Photochemistry and Photobiology, vol. 75, no. 4, pp. 382–391, 2002. View at Publisher · View at Google Scholar · View at Scopus