Research Article

Innovations and Challenges by Applying Sublingual Laser Blood Irradiation in Juvenile Idiopathic Arthritis

Table 2

Evolution from baseline of ACR core set data at the end of the sublingual laser blood irradiation.

Variable Group I ( = 36)Group II ( = 36)Group III ( = 33)
BaselineWeeks 24BaselineWeeks 24BaselineWeeks 24

ACR Pedi 30 response number (%)30 (83.33)20 (55.55) 19 (57.57)

ACR core set of variables
Number of joints with active arthritis7.58 ± 2.323.94 ± 1.14 ( = 0.001)7.5 ± 1.166.83 ± 1.23 ( = 0.02)7.42 ± 2.666.66 ± 1.21 ( = 0.13)
Number of joints with limited range of motion17.63 ± 5.319.30 ± 2.81 ( = 0.001)17.69 ± 14.613.80 ± 8.00 ( = 0.16)17.09 ± 3.6615.46 ± 2.65 ( = 0.04)
Physician's global assessment of overall disease activity56.11 ± 10.7631.25 ± 9.05 ( = 0.001)55.15 ± 13.2247.87 ± 12.69 ( = 0.01)56.66 ± 7.5251.46 ± 9.85 ( = 0.01)
Parent of patient global assessment of overall well-being58.05 ± 1.0433.88 ± 0.33 ( = 0.001)52.22 ± 13.0146.66 ± 13.90 ( = 0.09)60.30 ± 11.6953.46 ± 14.9 ( = 0.03)
CHAQ-DI score1.69 ± 0.681.05 ± 0.15 ( = 0.001)1.55 ± 0.561.22 ± 0.50 ( = 0.01)1.50 ± 0.541.20 ± 0.60 ( = 0.03)
ESR (mm/hr)42.38 ± 23.3517.58 ± 0.98 ( = 0.001)42.22 ± 6.9238.55 ± 6.85 ( = 0.02)41.83 ± 10.2836.80 ± 6.50 ( = 0.02)