Assessment of Bioprocess Development-Based Modeling and Simulation in a Sustainable Environment
Table 2
Input requirement and simulation.
Procedure
Input of user
Output simulation
Complete process
(i) Selection of batch or continuous operations (ii) Selection of liquid or solid and intra or extracellular products (iii) Selection based on the growth of anaerobic or aerobic biomass (iv) User-defined product quantity
(i) Energy and material requirement (ii) Categorizing the waste material (iii) Recovery and product purity
Sterilization
(i) Media sterilization
(i) Energy and material requirement
Bioreaction
(i) Growth rates, the concentration of biomass, and yield coefficients are required (ii) Maintenance calculation is included for selection
(i) Microbial growth prediction (ii) Requirements of antifoam and agitation
Waste treatment
(i) Waste treatment selection
(i) Chemical oxygen demand
Cooling
(i) Relevant cooling is included
(i) Energy and material requirement
Downstream
(i) From the built-in model, the downstream is specified
