Combined Application of 17-Estradiol and Progesterone Enhance Vascular Endothelial Growth Factor and Surfactant Protein Expression in Cultured Embryonic Lung Cells of Mice
Figure 3
Quantitative
analysis of VEGF gene expression in central lung fibroblasts treated for 48 hours
with E2-8 M and P-8 M alone or in combination. Values were
normalized against a housekeeping gene (HPRT) and expressed as % of controls.
Note that only the combined application of both hormones significantly
increased VEGF expression in central lung fibroblasts. Also note that the
application of dexamethasone (D) had similar effects on VEGF expression. control versus
E2/P-8 M, control versus D-8 M.
