Clinical Study
Fosfluconazole for Antifungal Prophylaxis in Very Low Birth Weight Infants
Table 1
Characteristics of the patients’ risk factors for invasive fungal infection.
| | Baseline characteristics () | | | | Birth weight-g | | | | Mean (range) | | (615–1466) | | Gastational age-wk | | | | Mean (range) | | (24.5–36.5) | | Male/Female sex-no. | 12/11 | | | Antinatal steroids-no. (%) | 13 | (57) | | Antinatal antibiotics-no. (%) | 9 | (39) | | Rupture of membranes 24 hr | | | | before delivery-no. (%) | 4 | (17) | | Born at study hospital-no. (%) | 22 | (96) | | Vaginal delivery-no. (%) | 5 | (22) | | APGAR score | | | | 1 min | | | | 5 min | | | | Age at enrollment | | | | 24 h | 18 | | | 24–48 h | 5 | | | Duration of prophylaxis | | | | Mean (range) | | (3–35) | | Treatment received-no. (%) | | | | Steroids | 6 | | | Ampicillin and Aminoglycosides | 19 | | | Cephalosporins | 2 | | | Carbapenems | 2 | | | Duration of antibiotics therapy-days | | | | Mean (range) | | (4–12) | | Vascular access-no. (%) | | | | Central vein | 23 | (100) | | Umbiliical | 1 | (4) | | Peripheral arterial | 8 | (35) |
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*
values are means ± SD. **The APGAR score ranges from 0 to 10, with higher scores indicating better functioning
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