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Author | Year reported | Sex | Age (years) | Country | Presentation | MRI/CT | Previous HIV- related event | HAART regimen | CD4 T-cell % or count (cell/L) | Viral load (copies/mL) | Outcome |
| Baseline | Nearest to episode | Baseline | Nearest to episode |
|
Oberdorfer et al. | 2009 | M | 9 | Thailand | Right hemiplegia | Frond-like hypodense lesion at the left frontal lobe | None | Initially nothing then AZT, 3TC, NVP | 0.21 | 0.21 | 185 976 | 185 976 | Dead |
Liptai et al. | 2007 | M | 15 1/2 | Hungary | Dizzy, diplopia, clumsy right hand, unsteady gait | Large, nonenhancing lesion of the right cerebellar heimsphere with a slight mass effect | None reported | Initially AZT, ddl then refused HAART | 37 | 10.5 | 2900 | 256 000 | Dead |
Shah and Chudgar. | 2005 | F | 8 1/2 | India | Right-sided dystonia, inability to talk, eat, or sit | Asymmetrical subcortical, right frontoparietal, left occipitoparietal and left vasal ganglia lesions | Generalized tonic clonic seizures and loss of consciousness | Initially nothing then AZT, 3TC, EFV, NLF | | 320 | | | Alive, still has dystonia |
Robinson et al. | 2004 | M | 17 | USA | Dysarthric speech, facial palsy | Multiple confluent areas of high signal and fluid attenuated inversion recovery in the corona radiata bilaterally | Pneumocystis jiroveci pneumonia | Initially AZT, 3TC then d4T, NVP, lopinavir/ ritonavir then included cidofovir | 3 | 3 | 10–90 000 | 29 100 | Stable, wide-based gait, dysarthria, right-sided tongue deviation |
Nuttall et al. | 2004 | M | 12 | South Africa | Acute cerebellar dysfunction, hemiparesis | Nonenhancing low density lesion in the left cerebellar hemisphere | Growth failure, chronic lung disease | d4T, 3TC, efavirenz | 1.08 | 5.45 | 96 000 | Undetectable | Stable, mild cerebellar dysfunction |
Inui et al. | 1999 | M | 12 | Jaban | Left upper extremity weakness | White matter lesions of the right frontal, parietal and occipital lobes | Candida stomatitis | AZT then ritonavir and 3TC added | | 9.5 | | 7600 | Stable, left hemiparesis |
Araujo et al. | 1997 | M | 10 | Brazil | Subacute cerebellar dysfunction, dementia | Focal nonenhancing area of low attenuation in the cerebellum | None reported | | | | | | |
Morriss et al. | 1997 | M | 7 | USA | Decreased activity, slurred speech, ataxia | Confluent, nonenhancing, low density lesion in the right cerebellar white matter, middle cerebellar peduncle and dorsolateral pons | Candida esophagitis | ddc | | 0 | | | Death |
Whiteman et al. | 1993 | M | 10 | USA | | | | | | | | | |
F | 12 | USA | | Increased signal intensity in the basal ganglia and corona radiata bilaterally | | | | | | | |
Berger et al. | 1992 | F | 13 | USA | Dysarthria, paresthesias of tongue and chin | Sinusitis and hyperintense signals in the basal ganglia | Oral candidiasis | AZT | 421 | 7 | | | Death |
M | 10 | USA | Facial palsy | Left frontal lobe lesion | Pneumocystis jiroveci pneumonia | AZT | 100 | | | | Death |
Vandersteenhoven et al. | 1992 | M | 7 | USA | Decreased activity, left hemiparesis, falling | Bilateral confluent abnormal white matter hyperintensity in the region of the right subcortical/ periventricular region | None reported | Initially nothing then AZT | | 390 | | | Death |
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