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International Journal of Pediatrics
Volume 2010 (2010), Article ID 265146, 8 pages
Research Article

Mortality in Extremely Low-Birth-Weight Neonates in México City (1985–2009)

1Unidad de Cuidados Neonatales, Hospital Español de México, Ejercito Nacional 613, C-302 colonia Granada, CP 11520, Mexico
2Departamento de Postgrado, Escuela de Medicina Universidad La Salle México, Fuentes #17, esquina Av. San Fernando, colonia Tlalpan, CP 14000, Mexico
3Unidad de Investigación en Epidemiología Clínica, UMAE Hospital de Pediatría CMN siglo XXI, Instituto Mexicano del Seguro Social, Avenida Cuauhtemoc 330 colonia Doctores, CP 06720, Mexico

Received 2 August 2010; Revised 23 September 2010; Accepted 13 October 2010

Academic Editor: Frans J. Walther

Copyright © 2010 José Iglesias-Leboreiro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To analyze 25 years of mortality of extremely low-birth-weight (ELBW) neonates (≤1000 g) in a private hospital in Mexico City and to establish the current viability limit for ELBW neonates. Methods. We designed a prospective observational study of all ELBW neonates born between 1985 and 2009. Neonatal mortality, early neonatal mortality, and the 120-day mortality rate were analyzed in 5-year intervals by two categories of birth weight (501–750 g and 751–1000 g). Results. Among the 50,823 total births, 158 were ELBW (3.1 per 103). Neonatal mortality (death ≤28 days) decreased for the 501–750 g neonates from 88.9% (1985–1989) to 55.6% (2005–1999) ( ) and for 751–1000 g neonates also decreased from 50% to 5.3% ( ). The 120-day mortality for neonates over 500 g diminished: 501–750 g neonates, 88.9% to 61.1% ( ) and for 751–1000 g neonates, 62.5% to 15.8% ( ). The highest viability limit was established in neonates who weighed ≥650 g and were ≥26 weeks in gestational age. Conclusions. The survival of ELBW neonates has improved in Mexico particularly in private hospitals, and it was more evident over the years 2004–2009. These data suggest that it is possible to increase the ELBW neonates survive in developing counties.