Clinical Study
Use of Nebulized Amphotericin B in the Treatment of Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis
| | Current age (years) | Age at (months) | Age at first ABPA diagnosis (years) | Sweat Cl (meq/l) | Genotype | Airway bacterial pathogens during ABPA | Indication for inhaled AMB | Other medica issues |
| 1 (f) | 7 | 11 | 5.5 | 106 | g.3464_3471dup TCATTGCT and V1198M | SA, SM, AX, Chronic PA (age 6) | 1 | ICS | 2( f) | 11 | 4 | 8 | 85 | F508del/F508del | SA, AX, | 1, 2 | ICS, Nissen | 3(m) | 13 | 2 | 8 | 90 | F508del/? | B. cepacia (age 8) | 2, 3 | | 4 (f) | 16 | 7 | 10 | 98 | F508del/R553X | Chronic PA (age 10), MAC (age 11) | 2, 3, 4 | MAC, gastrostomy, DM | 5 (f) | 19 | 36 | 7 | 120 | F508del/F508del | SA, HI, SM | 2, 3 | DM | 6 (f) | 20 | 1 (NS) | 11 | ? | F508del/F508del | Chronic PA (age 16) | 2, 3 | Nissen | 7 (f) | 20 | At birth | 9 | 95 | F508del/F508del | Chronic PA (age 5) | 2, 3 | MI, DM |
|
|