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International Journal of Pediatrics
Volume 2010 (2010), Article ID 580897, 5 pages
Clinical Study

Relationships of Cardiorespiratory Fitness with Metabolic Risk Factors, Inflammation, and Liver Transaminases in Overweight Youths

1Service de Pédiatrie, Centre Hospitalier de Bayeux, 14400 Bayeux, France
2Service de Pédiatrie, CHU de Caen, 14000, Caen, France
3Institut Régional de Médecine du Sport, CHU de Caen, 14000, Caen, France

Received 9 January 2010; Revised 4 May 2010; Accepted 2 June 2010

Academic Editor: Lars B. Andersen

Copyright © 2010 Dominique Bouglé et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The aim of this study was to assess the relationships of fatness and fitness with metabolic risk factors, including liver transaminases and inflammation in obese youth, taking in account gender, age, and pubertal stage. 241 children were studied (135 girls), age years ( ), Body Mass Index z score . For girls, was significantly associated with insulin ( ), Insulin resistance (HOMA-IR) ( ), and ALT ( ); a relationship was displayed between fibrinogen and age and % fat mass (FM) ( ); for boys, relationships were found between and diastolic blood pressure and triglycerides; independent associations were also found between age and insulin, HOMA-IR and HDL cholesterol; fibrinogen and sedimentation rate were related ( ) with %FM. Their relationships are observed from young age and increase with the continuous increase of factors. This supports the need to treat overweight as soon as it is detected; improving CRF is one of the ways which could be used to prevent the complications of obesity.