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International Journal of Pediatrics
Volume 2010, Article ID 670640, 7 pages
Review Article

Exercise Training in Children and Adolescents with Cystic Fibrosis: Theory into Practice

1Children's Health and Exercise Research Centre, School of Sport and Health Sciences, University of Exeter, Exeter EX1 2LU, UK
2Division of Pulmonary Medicine, University Hospital Zurich, 8091 Zurich, Switzerland

Received 19 January 2010; Revised 31 May 2010; Accepted 23 August 2010

Academic Editor: Patricia A. Nixon

Copyright © 2010 Craig A. Williams et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Physical activity and exercise training play an important role in the clinical management of patients with cystic fibrosis (CF). Exercise training is more common and recognized as an essential part of rehabilitation programmes and overall CF care. Regular exercise training is associated with improved aerobic and anaerobic capacity, higher pulmonary function, and enhanced airway mucus clearance. Furthermore, patients with higher aerobic fitness have an improved survival. Aerobic and anaerobic training may have different effects, while the combination of both have been reported to be beneficial in CF. However, exercise training remains underutilised and not always incorporated into routine CF management. We provide an update on aerobic and anaerobic responses to exercise and general training recommendations in children and adolescents with CF. We propose that an active lifestyle and exercise training are an efficacious part of regular CF patient management.