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International Journal of Pediatrics
Volume 2010, Article ID 825079, 6 pages
http://dx.doi.org/10.1155/2010/825079
Case Report

Extended Infusion of Dexmedetomidine to an Infant at Sixty Times the Intended Rate

1Department of Anesthesia, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115 , USA
2Department of Anesthesia, Perioperative, and Pain Medicine, Children's Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA

Received 30 June 2010; Accepted 6 August 2010

Academic Editor: Savithiri Ratnapalan

Copyright © 2010 Bryan A. Max and Keira P. Mason. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Dexmedetomidine is an 𝛼 2 adrenergic agonist which has recently been approved in the United States for procedural sedation in adults. This report describes an infant who inadvertently received an intravenous infusion of dexmedetomidine at a rate which was 60 times greater than intended. We describe the hemodynamic, respiratory, and sedative effects of this overdose.