Clinical Study

Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial

Table 3

Cardiometabolic biomarkers at baseline and at 10 months for the intervention and control groups with all intervention subjects included regardless of attendance at the PA sessions (unadjusted mean [SD]).

VariableBaseline10 MonthsAdjusted change (SE)* 𝑃 value
InterventionControlInterventionControl

Insulin, pmol/L119.4 (84.8)101.4 (59.9)130.6 (79.7)122.4 (57.1)−3.6 (8.9)0.69
Glucose, mmol/L4.89 (0.39)4.91 (0.43)4.85 (0.37)4.89 (0.38)−0.03 (0.06)0.63
SBP, mm Hg104.1 (7.5)102.4 (9.1)105.1 (8.3)103.8 (7.6)0.5 (1.0)0.64
DBP, mm Hg59.0 (5.6)59.5 (5.7)58.3 (6.5)58.8 (5.4)−0.3 (0.8)0.72
HR, bpm79.6 (9.2)79.8 (8.9)74.1 (8.9)76.9 (8.3)−2.7 (1.1)0.01
TC, mmol/L4.18 (0.83)4.15 (0.70)4.01 (0.74)4.15 (0.67)−0.15 (0.09)0.08
TG, mmol/L0.66 (0.30)0.63 (0.30)0.77 (0.37)0.71 (0.32)0.04 (0.05)0.46
HDLC, mmol/L1.34 (0.32)1.29 (0.28)1.36 (0.31)1.34 (0.31)−0.01 (0.04)0.73
LDLC, mmol/L2.67 (0.85)2.67 (0.69)2.47 (0.70)2.67 (0.75)−0.20 (0.10)0.04
LP(a), mg/dL45.5 (30.1)50.6 (42.8)47.8 (31.1)57.3 (48.1)−4.48 (3.59)0.21
LDL size, nm26.1 (0.69)26.2 (0.69)25.7 (0.82)25.8 (0.72)−0.09 (0.14)0.50
%HDL236.9 (20.3)36.7 (20.2)36.1 (20.3)35.8 (17.6)0.17 (3.30)0.96
ApoA1, mg/dL132.8 (32.3)124.3 (22.7)126.2 (22.1)125.3 (20.7)−1.31 (3.68)0.72
ApoB, mg/dL77.6 (29.9)77.3 (26.1)71.9 (26.6)74.1 (21.9)−2.3 (4.3)0.60
ApoCIII, ng/mL12.0 (3.8)11.4 (3.9)11.1 (4.2)11.5 (4.3)−0.62 (0.69)0.37
ApoE, ng/mL5.26 (1.49)5.03 (1.75)5.04 (1.56)4.78 (1.56)0.09 (0.20)0.66
CRP, ng/mL757.3 (1571.0)694.2 (883.6)597.9 (1333.7)795.8 (1120.5)−245.8 (145.2)0.09
Fibrinogen, mg/dL2.72 (0.51)2.77 (0.55)2.89 (0.50)2.91 (0.60)0.02 (0.08)0.83

SD: standard deviation; SBP: systolic blood pressure; DBP: diastolic blood pressure; HR: heart rate; TC: total cholesterol; TG: triglycerides; HDLC: high-density lipoprotein cholesterol; LDLC: low-density lipoprotein cholesterol; Lp(a): lipoprotein(a); VLDL: very low-density lipoprotein; Apo: apolipoprotein; CRP: C-reactive protein.
*Change estimates and standard errors (SE) are the differences between intervention and control groups adjusted for age and baseline value.
Intervention 𝑁 = 7 4 , Control 𝑁 = 6 0 .
Intervention 𝑁 = 1 1 8 , Control 𝑁 = 8 2 .