Clinical Study

Pulmonary Effects of Neonatal Hydrocortisone Treatment in Ventilator-Dependent Preterm Infants

Table 2

Respiratory characteristics.

CharacteristicsTotal ( ๐‘› = 5 5 ) %

Duration of ventilation (days)bโ€ƒโ€ƒ15.0 (5โ€“69) *
HFOV before treatmentc34.061.8
Postnatal age at start of HC (days)b11 (7โ€“44)
Duration of HC (days)d21.0 (9.0)
HC dose (mg/kg mean weight)d56.9 (28.2)
Extubation after start HC (days)d4.0 (4.0)
IRDSc
โ€ƒโ€ƒโ€ƒGrades I-II2341.8
โ€ƒโ€ƒโ€ƒGrades III-IV3258.2
Surfactantc
โ€ƒโ€ƒโ€ƒNo610.9
โ€ƒโ€ƒโ€ƒYes4989.1
Pneumothoraxc1221.8

Data are shown as bmedian (range), c ๐‘› or dmedian (interquartile range).
HFOV: high frequency oscillation ventilation; HC: hydrocortisone; IRDS: infant respiratory distress syndrome.
*In one case it took 69 days to wean the child from ventilator because of ongoing sepsis.