Clinical Study

Outcomes of Neonatal Candidiasis: The Impact of Delayed Initiation of Antifungal Therapy

Table 2

Antibacterial use: comparison between mortality and survivor groups.

Nonsurvivors
š‘› = 2 2
Survivors
š‘› = 4 1
š‘ƒ value

Days on antibacterial drugs before first positive fungal culture: mean36.317.30.002
Total days on antibacterial drugs: mean63.9400.006
Antibacterial agents used before invasive fungal infection
ā€ƒGlycopeptides (vancomycin) (%)20 (91)28 (68)0.06
ā€ƒAminoglycosides (amikacin, gentamicin, tobramycin) (%)18 (82)29 (71)0.34
ā€ƒ3rd generation cephalosporins (cefotaxime, ceftazidime) (%)21 (95)26 (63)0.003
ā€ƒCarbapenem (imipenem/cilastatin, meropenem) (%)8 (36)8 (19.5)0.16
ā€ƒAnaerobic (clindamycin, metronidazole) (%)6 (27)6 (15)0.32