International Journal of Pediatrics / 2012 / Article / Tab 1

Review Article

It Takes a Mouth to Eat and a Nose to Breathe: Abnormal Oral Respiration Affects Neonates' Oral Competence and Systemic Adaptation

Table 1

Distribution of myosin heavy chain (MHC) isoforms in selected oral (digastric, masseter) and nasal (levator) muscles in rats exposed to an early episode of forced oral breathing (CN group) and in control rats [74]. The different MHC isoforms were characterized on PND 11 and 90 (for key to the functions of the different MHC isoforms, see the text). Short-term nasal obstruction, that is forced oral breathing, leads to long-term orofacial muscle fibre adaptation. We observed increases in MHC neonatal and adult type I isoforms in muscles involved with oral breathing, digastric, and masseter, in CN group versus control on PND11. No changes were observed in the levator muscle involved with nasal breathing on PND 11. There are increases in MHC adult type IIb isoforms in muscle involved with oral breathing, masseter, and in muscle involved with nasal breathing, levator, in CN group versus control on PND 90. Values are given as percentages of total MHC and comparisons were then made using -test with the Bonferroni correction.

MHC isoformsembneoIIIaIIxIIb

On PND 11
 CN group
 Control group

On PND 90
 CN group
 Control group

*Significantly different from control group at = −10.37 to 26.03, to .

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