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International Journal of Pediatrics
Volume 2012, Article ID 237360, 8 pages
Review Article

Kidney Disease and Youth Onset Type 2 Diabetes: Considerations for the General Practitioner

1Department of Pediatrics and Child Health, University of Manitoba, 840 Sherbrook Street, Winnipeg MB, Canada R3A 1S1
2Section of Nephrology, Department of Pediatrics and Child Health, Children’s Hospital of Winnipeg, FE009 840 Sherbrook Street, Winnipeg, MB, Canada R3A 1S1

Received 2 August 2011; Accepted 11 October 2011

Academic Editor: Jyothsna Gattineni

Copyright © 2012 Allison B. Dart et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Youth onset type 2 diabetes (T2DM) continues to increase worldwide, concomitant with the rising obesity epidemic. There is evidence to suggest that youth with T2DM are affected by the same comorbidities and complications as adults diagnosed with T2DM. This review highlights specifically the kidney disease associated with youth onset T2DM, which is highly prevalent and associated with a high risk of end-stage kidney disease in early adulthood. A general understanding of this complex disease by primary care providers is critical, so that at-risk individuals are identified and managed early in the course of their disease, such that progression can be modified in this high-risk group of children and adolescents. A review of the pediatric literature will include a focus on the epidemiology, risk factors, pathology, screening, and treatment of kidney disease in youth onset T2DM.