Research Article
Off-Label Medicine Use in Pediatric Inpatients: A Prospective Observational Study at a Tertiary Care Hospital in India
Table 4
Most frequently prescribed off-label medicines.
| Sr.
number | System | Off-label medicine use (%) | Off-label category | Quality of
evidence | Strength of
recommendation |
| | 1 | Alimentary tract and metabolism | Ondansetron (100%) | Indication | Strong | High | | 2 | Respiratory system | Phenylephrine (91%) | Age, dose | Moderate | Medium | | 3 | Respiratory system | Dextromethorphan (90%) | Age, dose | Moderate | Medium | | 4 | Respiratory system | Chlorpheniramine (88%) | Dose | Moderate | Medium | | 5 | Anti-infectives for systemic use | Ceftriaxone (81%) | Dose | Strong | High | | 6 | Nervous system | Lorazepam (80%) | Indication | Strong | High | | 7 | Respiratory system | Ipratropium (79%) | Age, Dose | Strong | High | | 8 | Anti-infectives for systemic use | Amikacin (75%) | Dose | Strong | High | | 9 | Respiratory system | Salbutamol (75%) | Age, dose | Strong | High | | 10 | Nervous system | Paracetamol (56%) |
Age, dose | Moderate | High |
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