Neonatal Thrombocytopenia after Perinatal Asphyxia Treated with Hypothermia: A Retrospective Case Control Study

Table 2

Hematologic results of the study population.

	Hypothermia	Control group	value	OR [95% CI]
	group
Platelet count/transfusions
Platelet count <150 × 10^9/L*	43 (80%)	27 (59%)	.02	2.75 [1.14–6.66]
Platelet count at birth—×10^9/L*	154 (77)	157 (81)	.90	1.00 [0.99–1.01]
Lowest platelet count in the first week after birth*	97 (62)	125 (78)	.06	0.99 [0.99–1.00]
Day lowest platelet count*	4.1 (1.8)	2.9 (1.4)	<.001	1.58 [1.21–2.06]
Neonates requiring platelet transfusions— (%)	15 (28%)	10 (22%)	.49	1.39 [0.55–3.47]
Number. of platelet transfusions per	0.00 (1)	0.00 (0)	.94	0.99 [0.74–1.32]
neonate**
Coagulation disorders/FFP transfusions
PT—seconds*	25.3 (15.0)	21.2 (16.7)	.27	1.02 [0.98–1.06]
INR*	1.8 (1.1)	1.8 (1.5)	.96	0.99 [0.69–1.43]
APTT—seconds*	50.0 (20.1)	42.6 (23.8)	.16	1.02 [0.99–1.04]
Fibrinogen—gram/L*	1.6 (0.8)	2.0 (0.9)	.08	0.60 [0.34–1.07]
Neonates requiring FFP	13 (24%)	8 (17%)	.41	1.51 [0.56–4.03]
transfusions— (%)
Number of FFP transfusions per	0.00 (0)	0.00 (0)	.81	0.95 [0.62–1.45]
neonate**

PT: prothrombin time; INR: international normalized ratio; APTT: activated partial thromboplastin time; FFP: fresh frozen plasma.
**Value given as median (IQR).