Research Article

High Dose Dexmedetomidine: Effective as a Sole Agent Sedation for Children Undergoing MRI

Table 2

Outcomes with DEX group—clinical measures.

Dex A ()Dex B ()Dex C () value

Oxygen liters/min 0.87 (0.48) 0.99 (0.56)1.20 (0.61)<0.0001*
Dose (mcg) 35.96 (17.37) 36.20 (10.38)26.88 (17.58)<0.0001*
DBP (initial) 66.28 (11.54) 67.91 (10.81)65.29 (13.63) 0.2785
DBP (vital min) 39.75 (9.10) 39.52 (8.48)40.34 (9.34) 0.8416
DBP (vital max) 80.29 (10.94) 81.38 (10.60)84.32 (13.61) 0.0264*
SBP (initial)112.50 (13.95)111.93 (12.17)113.10 (13.52) 0.8234
SBP (vital min) 84.61 (8.93) 83.60 (9.84)84.91 (10.75) 0.5570
SBP (vital max)122.66 (12.69)122.17 (11.14)124.78 (14.13) 0.2311
HR (initial) 99.86 (19.11) 103.16 (20.11)101.40 (21.22) 0.3277
HR (vital min) 72.00 (13.94) 70.08 (12.49)72.61 (14.50) 0.3559
HR (vital max)110.69 (21.66)111.12 (21.55)114.97 (22.80) 0.1873
Resp. (initial) 20.45 (3.43) 20.36 (4.14)21.24 (4.06) 0.1343
Resp. (vital min) 15.64 (4.10) 15.97 (5.42)15.31 (4.24) 0.5413
Resp. (vital max) 24.27 (5.07) 25.84 (8.59)26.25 (7.78) 0.00067
SPO2 (initial) 99.11 (1.14) 99.07 (1.12)98.80 (1.40) 0.0548

Values are means (standard deviations); values are from ANOVAs.
MTD: time to discharge, DBP min: lowest diastolic blood pressure, DBP max: highest diastolic blood pressure, SBP min: lowest systolic blood pressure, SBP max: highest systolic blood pressure, HR min: lowest heart rate, and HR max: highest heart rate.
*Significant association at .