Enteral L-Arginine and Glutamine Supplementation for Prevention of NEC in Preterm Neonates
Table 2
Comparison between NEC negative and NEC positive patients.
NEC negative
NEC positive
Odds ratio
95% CI
Number = 68
Number = 7
GA (mean ± SD)
31.71 ± 2.05
28.86 ± 2.04
0.001*
0.530
0.3405 to 0.8240
WT (mean ± SD)
1.43 ± 0.23
1.11 ± 0.18
0.001*
0.000
0.0000 to 0.0758
Age on start (mean ± SD)
2.67 ± 1.52
1.57 ± 0.79
0.064
0.461
0.1896 to 1.1182
Increment of milk [number (%)]
≤20 cc/kg/day (: 64)
58 (85.3%)
6 (85.7%)
0.976
0.967
0.1049 to 8.9075
>20 cc/kg/day (: 11)
10 (14.7%)
1 (14.3%)
MOD [number (%)]
NVD
10 (14.7%)
2 (28.6%)
0.352
0.431
0.0733 to 2.5353
CS
58 (85.3%)
5 (71.4%)
Gender [number (%)]
Female
37 (54.4%)
4 (57.1%)
0.890
0.895
0.1860 to 4.3079
Male
31 (45.6%)
3 (42.9%)
Arginine 1 (ng/mL) (mean ± SD)
8.12 ± 2.78
8.93 ± 4.28
0.497
1.090
0.8523 to 1.3934
Glutamine 1 (mM) (mean ± SD)
0.20 ± 0.10
0.23 ± 0.20
0.481
1.110
0.1754 to 1.231
GA: gestational age. WT: weight. MOD: mode of delivery. NVD: normal vaginal delivery. CS: Caesarean section. 1: at time of enrollment. *Highly significant.
