Research Article
Growth and Neurodevelopmental Outcome in Preterm LBW Infants with Sepsis in India: A Prospective Cohort
(a) Baseline variables of the studied patients |
| Variable | () |
| Mean gestation (weeks) | 30.76 (SD ± 2.03) | Singleton | 77 (81.91%) | Primi (refers to first gestation) | 42 (44.68%) | APH | 05 (05.30%) | Maternal diabetes | 09 (09.59%) | Maternal hypertension | 61 (64.89%) | Maternal hypothyroid | 16 (17.02%) | Maternal rupture of membranes | 19 (20.21%) | Oligohydramnios | 27 (28.72)% | Steroid covered | 81 (86.17%) | Caesarian section | 81 (86.17%) | Preterm labor | 21 (22.34%) | IUGR | 17 (18.08%) |
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APH: antepartum hemorrhage; IUGR: intrauterine growth retardation.
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(b) Baseline variables of the neonatal data |
| Variable | |
| Median birth weight (grams) | 1883 (IQR 1560–2360) | Median head circumference at birth (cm) | 28.5 (IQR 26–31) | Median length at birth (cm) | 37.69 (IQR 34–40) | Sex males | 48 (51%) | HMD | 55 (58.51%) | CPAP | 54 (57.44%) | Ventilation | 21 (22.34%) | Sepsis | 40 (42.55%) | Culture positive sepsis | 24 (25.53%) | Screen positive sepsis | 16 (17.02%) | NEC | 19 (20.21%) | Shock | 48 (51.06%) | Seizure | 8 (8.5%) | Hypoglycemia | 9 (9.57%) | Apnea | 14 (14.89%) | Anemia transfusion | 14 (14.89%) | PDA | 11 (11.72%) |
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BPD: bronchopulmonary dysplasia; PDA: Patent Ductus Arteriosus; NEC: necrotizing enterocolitis; HFO: high frequency oscillatory ventilation; SIMV: synchronized intermittent mandatory ventilation; HMD: hyaline membrane disease; CPAP: continuous positive airway pressure.
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(c) Baseline variables of infants at the time of discharge |
| Variable | Total () |
| Days to full feeds median (days) | 7.88 (SD ± 3.11) | Duration of hospital stay (days) | 17.67 (SD ± 10.63) | Discharge weight (grams) | 1999 (SD ± 114) | Discharge head circumference (cm) | 29.51 (SD ± 1.72) | Discharge length (cm) | 39.15 (SD ± 1.80) | ROP | 17 (18.08%) | ROP with LASER | 4 (4.25%) | Abnormal BERA | 12 (12.76%) | Abnormal NSG | 30 (31.91%) |
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ROP: Retinopathy of Prematurity.
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