Review Article

A Systematic Review of Pediatric and Adult In-Flight Medical Emergencies

Table 1

Summary of included studies that focused on in-flight medical emergencies.

Source (country)Purpose of the studyStudy designPopulation Age, sexGroup (n)Source of dataDuration

Moore et al. (USA)To determine the incidence and character of pediatric emergencies on commercial airline and to evaluate current in-flight medical kits.Observational retrospective reviewPediatricMean patient age
6.8 years,
Sex unknown
222Telemedicine database7 years

Rotta et al. (USA)To characterize in-flight pediatric fatalities onboard commercial airlinesRetrospective cohort studyPediatricMedian patient age 3.5 months
(range 1mo-15 yrs)
Female 50%
10Telemedicine database3.5 years

Hinkelbein et al. (Germany)To gather data on incidence, nature, and medical equipment use for in-flight emergenciesRetrospective analysis of secondary data (survey)Adult and PediatricMean patient age 54.1 years
(range 15-79 yrs)
Female 40.7%
54Physician members of an aerospace medical society1 month

Szmajer et al. (France)To analyze the causes and outcomes of in-flight emergency calls from a commercial airlineRetrospective studyAdult and PediatricMean patient age 41.12 years
(range 1- 84 yrs)
Female 37.7%
380Telemedicine database1 year

Matsumoto et al. (USA)To ascertain the incidence of in-flight psychiatric emergencies, their associated factors, and outcomes.Retrospective studyAdult and PediatricMean patient age
39.6 years
(range 10- 80 yrs)
Female 73%
1,375Telemedicine database1 year

Kesapli et al. (Turkey)To evaluate the incidence and status of urgent medical conditions, the attitudes of health professionals, the adequacy of medical kits and training of cabin crewRetrospective cohort studyAdult and PediatricMedian patient age 45 years
(range 0- >=86 yrs)
Female 53.2%
1,312Commercial airline database3 years

Peterson et al. (USA)To describe in-flight medical emergencies and the outcomes of these events.Retrospective cohort studyAdult and PediatricMean patient age
48 years
(range 14 days-100 yrs)
Sex unknown
11,920Telemedicine database2.8 years

Weinlich et al. (Germany)To identify which patients require diversion due to a medical incident on a commercial flightProspective studyAdult and PediatricMean patient age
58 years
(range <1 – 91 yrs)
Sex unknown
3,364Commercial airline database3 years

Urwin et al. (UK)To characterize medical emergencies on board of commercial flightsRetrospective reviewAdult and PediatricMean patient age
42 years
(range 1- 87 yrs)
Female 56%
273Telemedicine database5 years

Chan et al. (USA)To determine incidence, post-flight treatments, outcomes, morbidity, and mortality of in-flight medical emergenciesRetrospective studyAdult and PediatricMean patient age
46.6 years
Female 54.7%
744EMS, ED, and inpatient hospital records of in-flight medical emergencies from a major international airport1 year

Speizer et al. (USA)To evaluate the potential usefulness of any emergency medical kitRetrospective studyAdult and PediatricAge unknown
Female 50.8%
260ER, hospital, airport first-aid station medical records6 months

Delaune et al. (USA)To determine the incidence of each type of in-flight medical complaint, the appropriateness of medical kit contents, which factors lead to aircraft diversion, and which factors affect the appropriateness of the decision to divertObservational retrospective reviewAdult and PediatricNot reported2,279Telemedicine database1 year

Baltsezak (China)To characterize medical emergencies on board of commercial flightsRetrospective studyAdult and PediatricNot reported191Telemedicine database1 year

Hordinsky (USA)To characterize in-flight medical emergencies and efficacy of medical kit usageRetrospective reviewAdult and PediatricNot reported1,016Commercial airline database1 year

Alves et al. (USA)To gather data on outcomes and prognostic factors for victims of in-flight cardiac arrestRetrospective cohort studyAdultMean patient age 61.9 years
(SD 15.62)
Female 36.5%
394Telemedicine database10 years

Brown et al. (USA)To describe the characteristics and outcomes of AED use during in-flight emergenciesRetrospective descriptive studyAdultMean patient age
58 years
Female 36%
169Telemedicine database4.7 years

Hung et al. (UK)To provide description of in-flight medical emergencies and systematically examine predictors of medical flight diversions and deathsRetrospective cohort studyAdultAge unknown,
Female 53.9%
4,068Telemedicine database5 years

Page et al. (USA)To analyze the AED use on board of a commercial flightRetrospective cohort studyAdultMean patient age
58 years
Female 34%
200Commercial airline database2 years

Cottrell et al. (USA)To analyze the effectiveness of enhanced medical kit in treating in-flight emergencies on board of a commercial flightRetrospective review and survey studyAdultMean patient age
54 years (males)
48 years (females)
Female 43%
362Commercial airline database, hospital records, and patient and health care providers questionnaires1 year

Valani et al. (Canada)To determine the causes of in-flight medical diversions from a commercial airlineRetrospective reviewNot reportedNot reported220Telemedicine and commercial airline databases5 years

Quereshi et al. (UK)To analyze medical emergencies on board of single commercial airlineRetrospective reviewNot reportedNot reported507Commercial airline database6 months

Sirven et al. (USA)To analyze the frequency of neurologic events during commercial airline flights and to assess whether onboard emergency medical kits are adequate for such eventsRetrospective studyNot reportedNot reported2,042Telemedicine database5 years

Donaldson et al. (Australia)To analyze the types of medical emergencies encountered during commercial air travelRetrospective studyNot reportedNot reported454Commercial airline database1 year

Sand et al. (Germany)To document medically relevant emergencies in airline passengersRetrospective studyUnknownUnknown10,189Commercial airline database6 years

Sand et al. (Germany)To analyze different forms of documentation for in-flight medical emergencies use by commercial airlinesDocumentation analysisN/AN/A10 airlinesIn-flight medical emergency documentation forms from commercial airlinesUnknown