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International Journal of Pediatrics
Volume 2018, Article ID 9181497, 7 pages
https://doi.org/10.1155/2018/9181497
Research Article

Infants Born Large for Gestational Age and Developmental Attainment in Early Childhood

1Department of Epidemiology and Biostatistics, University of Western Ontario, London, ON, Canada
2Children’s Health Research Institute, Lawson Health Research Institute, London, ON, Canada
3Department of Pediatrics, University of Western Ontario, London, ON, Canada
4Department of Obstetrics and Gynecology, University of Western Ontario, London, ON, Canada

Correspondence should be addressed to M. Karen Campbell; ac.owu.hciluhcs@llebpmac.nerak

Received 23 August 2017; Accepted 28 November 2017; Published 1 January 2018

Academic Editor: Samuel Menahem

Copyright © 2018 Cairina E. Frank et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objectives. To investigate if an association exists between being born large for gestational age (LGA) and verbal ability or externalizing behaviour problems at ages 4-5 years. Method. A secondary analysis was conducted using the National Longitudinal Survey of Children and Youth, including singleton births in 2004-2005 followed till 4-5 years . LGA was defined as a birth weight > 90th percentile. Outcomes included poor verbal ability (scoring < 15th percentile on the Revised Peabody Picture Vocabulary Test) and externalizing behaviour problems (scoring > 90th percentile on externalizing behaviour scales). Multivariable logistic regression with longitudinal standardized funnel weights and bootstrapping estimation were used. Results. Infants born LGA were not found to be at increased risk for poor verbal ability (aOR: 1.16 and aOR: 0.83 for girls and boys, resp.) or externalizing behaviour problems (aOR: 1.24 and aOR: 1.24 for girls and boys, resp.). Social factors were found to impact developmental attainment. Maternal smoking led to an increased risk for externalizing behaviour problems (aOR: 3.33 and aOR: 2.12 for girls and boys, resp.). Conclusion. There is no evidence to suggest that infants born LGA are at increased risk for poor verbal ability or externalizing behaviour problems.