Research Article
Acute Kidney Injury in Pediatric Treated with Vancomycin and Piperacillin-Tazobactam in Tertiary Care Hospital
Table 3
Doses, frequency, and follow-up measures.
| | Factor | | |
| | Vancomycin dose (mg/kg/day) | Mean ± SD | 45.8 ± 14.1 | | | Median (IQR) | 45.0 (38.0-58.0) | | Vancomycin frequency n (%) | | | | Every 6 hours | | 172 (69.4%) | | Every 8 hours | | 70 (28.2%) | | Every 12 hours | | 4 (1.6%) | | Every 24 hours | | 2 (0.8%) | | Initial vancomycin trough level (mg/L) | Mean ± SD | 9 ± 5.2 | | | Median (IQR) | 8.1 (4.9-11.7) | | Piperacillin-tazobactam dose (mg/kg/dose) | Mean ± SD | 95.8 ± 24.5 | | | Median (IQR) | 100.0 (89.5-100.0) | | Piperacillin-tazobactam frequency n (%) | | | | Every 6 hours | | 5 (8.1%) | | Every 8 hours | | 57 (91.9%) | | Ceftazidime dose (mg/kg/dose) | Mean ± SD | 45.8 ± 9.2 | | | Median (IQR) | 50.0 (49.0-50.0) | | Ceftazidime frequency n (%) | | | | Every 8 hours | | 99 (100%) | | Ceftriaxone dose (mg/kg/dose) | Mean ± SD | 61.2 ± 31.0 | | | Median (IQR) | 50.0 (45.0-71.3) | | Ceftriaxone frequency n (%) | | | | Every 12 hours | | 10 (19.6%) | | Every 24 hours | | 41 (80.4%) | | WBC (x 109/L) 48 hours | Mean ± SD | 8.5 ± 5.2 | | | Median (IQR) | 8.0 (5.0-11.4) | | Days of therapy | Mean ± SD | 7.2 ± 7.2 | | | Median (IQR) | 5.0 (4.0-8.0) |
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