Do Maternal Vitamin D Levels Influence Vitamin D Levels in Preterm Neonates?

Table 5

Factors associated with vitamin D status at different time points in preterm infants.

Variable	Vitamin D insufficiency/deficiency (p value)
Low serum maternal vit D	P<0.001
(<50nmol/L)	P=0.006^#
Ethnicity	0.003##
Season-Winter/Autumn	0.954
GA	0.382
Birth weight	0.646
Male sex	0.986
Sepsis	0.500
NEC	0.838

value at birth, #p value at 3-4 weeks, ##non-Caucasian. Sepsis definition (CDC definition): a neonate was considered to have a BSI if there was (1) a definite pathogen in blood culture OR (2) growth of a possible contaminant (e.g., coagulase-negative staphylococcus, CONS) in blood PLUS treatment with antibiotics ≥96 h (or death <96 h) PLUS. Growth of the same organism on repeat culture OR one or more abnormal laboratory markers (e.g., C-reactive protein >10 mg/L, immature: total neutrophil ratio >0.2) (definite infection) OR clinical features consistent with systemic infection (e.g., lethargy, apnoea, and significant change in respiratory condition) (clinical infection) [19, 20].