Unique Characteristics of Prepubertal Onset Systemic Lupus Erythematosus

Table 1

Characteristics and outcomes of systemic lupus erythematosus (SLE) patients according to age at onset of disease.

Characteristic, n (%) unless specified otherwise	Pre-pubertal	Peri-pubertal	Post-pubertal	P-value
	n=39	n=29	n=35
Age at disease onset (years)
Girls	≤ 8 (69%; n=27)	> 8 and <13	≥ 13(91%; n=32)	0.056
		(83%; n=24)
Boys	≤ 9 (31%; n=12)	>9 and <14	≥14 (8.6%; n=3)
		(17%; n=5)
Age, mean ± SD, years				<0.001
Sex ratio (F: M)	1: 2 (27:12)	1:5 (24:5)	1: 11 (32:3)	0.056
Region				<0.001
Sharqiya	61%; n=24	24%; n=7	14%; n=5
Batina	15%; n=6	24%; n=7	40%; n=14
Muscat	5.1%; n=2	28%; n=8	29%; n=10
Dhakhilia	5.1%; n=2	21%; n=6	11%; n=4
Dhahira	0	3.4%; n=1	2.9%; n=1
Dhofar	13%; n=5	0	0
Musandam	0	0	2.9%; n=1
Family history of SLE	25 (64%)	9 (31%)	7 (20%)	<0.001
degree	19 (49%)	4 (14%(	5 (14%)	0.001
DI ≥1	15 (39%)	12 (41%)	10 (29%)	0.520
Mortality	3 (7.7%)	1 (3.4%)	1 (2.9%)	0.626

SD: standard deviation; F: female; M: male; DI: damage index.