Unique Characteristics of Prepubertal Onset Systemic Lupus Erythematosus

Table 2

Clinical manifestations of systemic lups erythematosus (SLE) patients according to age at onset of disease.

Characteristics	Pre-pubertal	Peri-pubertal	Post-pubertal	P-value
n (%)	n=39	n=29	n= 35
Cutaneous	74.4% (29)	69%(20)	45.7%(16)	0.029
	UV (53.8%)	alopecia (27.6%)	alopecia (20%)
Nephritis	20 (51%)	10 (34%)	8 (23%)	0.039
Hematological	11 (28%)	19 (66%)	25 (71%)	<0.001
Arthritis	30 (77%)	19 (66%)	21 (60%)	0.281
Neurological	4 (10%)	6 (21%)	5 (14%)	0.500
Pulmonary	6 (15%)	4 (14%)	0	0.031
Serositis	8 (21%)	7 (24%)	3 (8.6%)	0.201
Constitutional symptoms	28 (72%)	21 (72%)	17 (49%)	0.063
SLEDAI (severe activity)	24 (61%)	18 (62%)	14 (40%)	0.110

SLDEDAI: Systemic Lupus Erythematosus Disease Activity Index.