Unique Characteristics of Prepubertal Onset Systemic Lupus Erythematosus

Table 4

Medications of systemic lupus erythematosus (SLE) patients according to age at onset of disease.

Medications, n (%)	Pre-pubertal	Peri-pubertal	Post-pubertal	P-value
	n=39	n=29	n=35
NSAIDS	20 (51%)	12 (41%)	11 (31%)	0.224
Hydroxychloroquin (HCQ))	38 (100%)	28 (97%)	34 (97%)	0.851
Prednisolone	39 (100%)	29 (100%)	28 (80%)	0.001
IVMP	20 (51%)	19 (66%)	27 (77%)	0.067
Azathioprine	27 (69%)	22 (76%)	24 (69%)	0.783
Methotrexate	10 (26%)	0	12 (34%)	0.001
Mycophenolate mofetil	25 (64%)	18 (62%)	25 (71%)	0.697
Cyclophosphamide	20 (51%)	15 (52%)	20 (57%)	0.861
Rituximab	6 (15%)	5 (17%)	15 (43%)	0.013
Immunoglobulin	3 (7.7%)	3 (10%)	7 (20%)	0.256

NSAIDs: nonsteroidal anti-inflammatory drugs; IVMP: intravenous methylprednisolone.
HCQ was missing in 1 patient under prepubertal.