Time to Relapse and Its Predictors among Children with Nephrotic Syndrome in Comprehensive Specialized Hospitals, Tigray, Ethiopia, 2019
Table 4
Bivariable and multivariate analysis output for children with nephrotic syndrome in comprehensive specialized hospitals of Tigray region, Northern Ethiopia, 2019 ().
Outcome status
Crude HR (95% CI)
Adjusted HR (95% CI)
Covariates
Category
Relapsed
Censored
Age (in years)
1-3
9
14
1.77 (0.78-4.00)
2.24 (0.86-5.83)
4-6
8
28
0.84 (0.36- 1.93)
2.65 (0.99-7.11)
7-9
24
32
1.52 (0.83-2.79)
1.33 (0.66-2.68)
>9
21
38
—
—
Residence
Urban
51
7
—
—
Rural
123
55
2.9 (1.30-6.40)
4 (1.49-10.76)
History of allergy
Yes
29
20
0.39 (0.22- 0.68)
1.18 (0.61-2.28)
No
145
42
—
—
Time to achieve remission (days)
0-7
19
4
—
—
8-14
80
21
1.63 (0.96-2.78)
0.90 (0.27-2.99)
>14
75
37
0.74 (0.37-1.48)
1.18 (0.37-3.76)
Duration of treatment
<8 weeks
39
16
0.65 (0.36-1.18)
0.74 (0 .37-1.50)
≥8 weeks
135
46
—
—
Albumin (g/dL)
≤1.5
43
34
4.14 (2.44-7.00)
3.51 (1.81-6.80)
>1.5
131
28
—
—
TGD
Normal
43
5
—
—
Borderline
95
28
4.6 (1.38-15.28)
1.66 (0.53-5.2)
High
36
29
9.78 (2.94-32.55)
3.37 (1.04-10.9)
Nutrition
Normal
128
30
—
—
Malnourished
46
32
3.39 (2.01-5.71)
3.44 (1.78-6.65)
Note: significant at 5% level of significance. Abbreviations: HR: hazard ratio; CI: confidence interval; g/dl: grams per deciliter; TGD: triglyceride.
