No Evidence of Abnormal Expression of Beta-Catenin and Bcl-2 Proteins in Pilomatricoma as One Clinical Feature of Tetrasomy 9p Syndrome

Figure 1

Histological findings of pilomatricoma in our patient. (a) H&E staining revealed a tumor composed of basaloid cells, ghost or anucleated shadow cells, and areas of cystic degeneration. The basaloid cells are darkly stained, round, or elongated with deeply basophilic nuclei. The ghost or anucleated shadow cells have abundant pale, eosinophilic cytoplasm with a clear central area. The latter are highly characteristic of pilomatricoma. (b) Immunohistochemical staining of beta-catenin in the patient’s pilomatricoma tissue showed no beta-catenin expression (left) and positive control (right). (c) Immunohistochemical staining of bcl2 in the patient’s pilomatricoma tissue showed no bcl2 expression (left) and positive control (right).

(a)

(b)

(c)