Comparing Watchful Waiting Approach vs. Antibiotic Therapy in Children with Nonsevere Acute Otitis Media: A Randomized Clinical Trial
Table 2
Clinical symptoms of the patients before and after intervention.
Before intervention
After intervention
Variables
Intervention (: 188)
Control (: 208)
value
Intervention (: 188)
Control (: 208)
value
Otalgia
94 (50%)
106 (51%)
>0.05
28 (15%)
59 (28%)
<0.01
Fever
170 (90%)
172 (83%)
<0.01
35 (19%)
92 (44%)
<0.01
Irritability
86 (46%)
86 (41%)
>0.05
19 (10%)
40 (19%)
<0.05
Vomiting
6 (3%)
9 (4%)
>0.05
9 (5%)
4 (2%)
>0.05
Diarrhea
10 (5%)
8 (4%)
>0.05
13 (7%)
5 (2%)
<0.05
Coryza
107 (57%)
118 (57%)
>0.05
6 (3%)
10 (5%)
>0.05
Cough
92 (49%)
106 (51%)
>0.05
4 (2%)
10 (5%)
>0.05
Pharyngitis
4 (2%)
1 (0.5%)
>0.05
0 (0%)
0 (0%)
—
Nasal congestion
15 (8%)
10 (5%)
>0.05
1 (0.5%)
0 (0%)
>0.05
Skin rash
21 (11%)
25 (12%)
>0.05
2 (1%)
0 (0%)
>0.05
Asthma
7 (4%)
10 (5%)
>0.05
0 (0%)
0 (0%)
—
Poor feeding
4 (2%)
1 (0.5%)
>0.05
0 (0%)
0 (0%)
—
Ear drum perforation
x
x
2 (1%)
1 (0.5%)
>0.05
Unilateral erythema of TM
104 (55%)
129 (62%)
>0.05
Bilateral erythema of TM
83 (44%)
78 (37%)
>0.05
Unilateral MEE
93 (49%)
111 (53%)
>0.05
Bilateral MEE
55 (29%)
59 (28%)
>0.05
MEE: middle ear effusion; TM: tympanic membrane. Statistically significant. Not assessed after 3 days. X: ear drum perforation cases were excluded at initiation of the study.
