Research Article
Comparing Watchful Waiting Approach vs. Antibiotic Therapy in Children with Nonsevere Acute Otitis Media: A Randomized Clinical Trial
Table 3
Association between treatment response and different factors.
| | Intervention (: 188) | Control (: 208) | value | | No | Yes | No | Yes |
| | Age | 6-23 months | 68 (74) | 24 (26) | 43 (44) | 54 (56) | <0.01 | | 2-6 years | 69 (72) | 27 (28) | 48 (43) | 63 (57) | | | Antibiotic in last 4 weeks | Yes | 78 (72%) | 31 (28%) | 57 (42%) | 79 (58%) | <0.01 | | No | 59 (75%) | 20 (25%) | 34 (47%) | 38 (53%) | <0.01 | | Pneumococcal vaccination | Yes | 3 (100%) | 0 (0%) | 1 (33%) | 2 (67%) | >0.05 | | No | 114 (56%) | 91 (44%) | 50 (27%) | 135 (73%) | <0.01 | | History of allergy | Yes | 16 (64%) | 9 (36%) | 5 (24%) | 16 (76%) | <0.01 | | No | 101 (55%) | 82 (45%) | 46 (27%) | 121 (73%) | <0.01 | | History of asthma | Yes | 8 (80%) | 2 (20%) | 1 (14%) | 6 (86%) | <0.01 | | No | 109 (55%) | 89 (45%) | 50 (28%) | 131 (72%) | <0.01 | | History of breastfeeding | Exclusive breastfeeding | 76 (56%) | 60 (44%) | 32 (25%) | 96 (75%) | <0.01 | | Formula-fed | 16 (57%) | 12 (43%) | 7 (29%) | 17 (71%) | <0.05 | | Both | 25 (61%) | 16 (39%) | 12 (33%) | 24 (67%) | <0.05 | | Child care type | Day care center | 31 (54%) | 26 (46%) | 17 (35%) | 31 (65%) | >0.05 | | Babysitter | 5 (62%) | 3 (38%) | 1 (10%) | 9 (90%) | <0.05 | | Mother | 81 (57%) | 62 (43%) | 33 (25%) | 97 (75%) | <0.01 | | Smoke exposure | Yes | 20 (54%) | 17 (46%) | 10 (33%) | 20 (67%) | >0.05 | | No | 95 (56%) | 74 (44%) | 39 (25%) | 117 (75%) | <0.01 | | Erythema of TM | Unilateral | 79 (76) | 25 (24) | 63 (49) | 66 (51) | <0.01 | | Bilateral | 57 (69) | 26 (31) | 27 (35) | 51 (65) | <0.01 | | MEE | Without effusion | 32 (80) | 8 (20) | 26 (68) | 12 (32) | >0.05 | | Unilateral | 70 (75) | 23 (25) | 47 (42) | 64 (58) | <0.01 | | Bilateral | 35 (64) | 20 (36) | 18 (31) | 41 (69) | <0.01 |
|
|
MEE: middle ear effusion; TM: tympanic membrane. Statistically significant. All patients did not refer for examination. |
