Neonatal Resuscitation Research Priorities in Low- and Middle-Income Countries

Table 1

2020 CoSTR topics reviewed and evidence evaluation process [14].

Sr. no.	Topic	Subtopic	Process	Studies from LMICs
1	Anticipation and preparation	Prediction of need of respiratory support in the delivery room	Evidence update	No
		Effect of briefing/debriefing following neonatal resuscitation	Scoping review	No
2	Initial assessment and intervention	Warming adjuncts	Evidence update	No
		Suctioning of clear fluid	Scoping review	No
		Tracheal intubation and suction of nonvigorous meconium-stained newborns	Systematic review	Yes
3	Physiological monitoring and feedback devices	Heart rate monitoring during neonatal resuscitation	Evidence update	No
4	Ventilation and oxygenation	Sustained inflation	Systematic review	Yes
		Positive end-expiratory pressure (PEEP) versus no PEEP	Evidence update	No
		Continuous positive airway pressure (CPAP) versus intermittent PPV	Evidence update	No
		T-piece resuscitator versus self-inflating bag for ventilation	Scoping review	Yes
		Oxygen for preterm resuscitation	2019 CoSTR publication	No
		Oxygen for term resuscitation	2019 CoSTR publication	No
5	Circulatory support	CPR ratios for neonatal resuscitation	Evidence update	No
		2-thumb versus 2-finger compressions for neonatal resuscitation	Evidence update	No
6	Drug and fluid administration	Epinephrine (adrenaline) for neonatal resuscitation	Systematic review	No
		Intraosseous versus umbilical vein for emergency access	Systematic review	No
		Volume infusion during neonatal resuscitation	Evidence update	No
		Sodium bicarbonate during neonatal resuscitation	Evidence update	No
7	Prognostication during CPR	Impact of duration of intensive resuscitation	Systematic review	No
8	Postresuscitation care	Rewarming of hypothermic newborns	Evidence update	No
		Induced hypothermia in settings with limited resources	Evidence update	Yes
		Postresuscitation glucose management	Evidence update	No