National Consensus for the Management of Acute Gastroenteritis in Jordanian Children: Consensus Recommendations Endorsed by the Jordanian Paediatric Society

Table 3

Pharmacological options as adjunct treatment to ORS for the management of paediatric AGE in Jordan.

Type	Dosage	Time	Notes
Ondansetron	4 mg	Single dose	Six months and older; Suspected AGE; Failed oral rehydration therapy
Diosmectite	4 sachets (3 g each) a day for 3 days, then 2 sachets (3 g each) per day	5 days	2 years and older
Racecadotril	1.5 mg/kg per administration; 3 times per day (plus one initial dose on day 1); (i) From 1 month to 9 months (less than 9 kg): 1 sachet (10 mg) per administration; (ii) From 9 to 30 months (about 9 to 13 kg): 2 sachets per administration	Up to 7 days	1 month and older
Anti-infective drugs	Pathogen-based, see Table 2	Pathogen-based, see Table 2	Consider in; (i) Age below 3 months; (ii) Chronic/serious underlying conditions; (i) Isolation/identification of certain pathogenic microorganisms; (ii) Bloody diarrhoea in sick children
Lactobacillus rhamnosus GG	≥10^10 CFU/day	5-7 days	All children
Saccharomyces boulardii	250-750 mg/day	5-7 days	All children
Zinc	10-20 mg	10-14 days	Use in children older than 6 months