Recombinant Human Trefoil Factor 3 Ameliorates Bowel Injury: Its Anti-Inflammatory Effect on Experimental Necrotizing Enterocolitis
Figure 1
Small intestinal histology in the neonatal rats treated as described in Section 2 (HE staining). (a) Control animal showing the normal intestinal villus architecture (score 0). (b) NEC animal treated with rhTFF3 by subcutaneous injection showing a slight histological injury (score 2): moderate separation of submucosa (arrow). (c) NEC animal with complete villous necrosis (score 4): severe separation of submucosa and loss of villi with necrosis (arrow). (HE, magnification 200.)
