Recombinant Human Trefoil Factor 3 Ameliorates Bowel Injury: Its Anti-Inflammatory Effect on Experimental Necrotizing Enterocolitis
Figure 3
Immunohistochemistry analysis using a polyclonal antibody for NF-B (Santa Cruz Biotech) in a small intestinal sample from (a) control animal: NF-B is barely detectable in the epithelium. (b) NEC animal: NF-B staining is pronounced in the nuclei of inflammatory cells (arrow). (c) NEC animal treated with rhTFF3 by subcutaneous injection for 3 days: NF-B staining is reduced in the epithelium. All the animals were decapitated and sampled at day 4. (SP, magnification 400.)
